{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T08:58:01Z","timestamp":1785574681883,"version":"3.56.0"},"reference-count":68,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adolescent depression is heterogeneous, yet many studies rely on aggregate symptom scores that may obscure meaningful differences in symptom presentation. Latent class analysis (LCA) offers a person\u2010centered approach for identifying symptom subgroups, but few studies have examined depressive symptom classes longitudinally with attention to social determinants of health (SDoH). This study identified depressive symptom classes among youth with depression and\/or suicidality, examined demographic, clinical, and socio\u2010ecological correlates of class membership, and evaluated changes in psychological outcomes over 6\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were 1,825 youth ages 8\u201320\u2009years who screened positive for depression, endorsed suicidal thoughts or behaviors, or were receiving treatment for depression. Baseline Patient Health Questionnaire for Adolescents (PHQ\u2010A) item responses were used to identify latent classes of depressive symptoms. Associations between class membership and sociodemographic characteristics, trauma exposure, health\u2010related social needs, treatment barriers, anxiety, suicidality and resilience were examined using chi\u2010square tests and analyses of variance. Mixed\u2010effect models evaluated changes in clinical symptoms and resilience across 6\u2009months of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A five\u2010class solution was identified: Somatic Symptoms (15.6%), No Symptoms (12.4%), Mild Symptoms (20.5%), Moderate Symptoms (27.8%), and High Symptoms (23.5%). Classes differed significantly by sex, trauma exposure, interpersonal safety concerns, treatment barriers, anxiety severity, suicidality, and resilience. In contrast, household income and basic resource insecurities did not differ significantly across classes. Longitudinally, depressive symptoms, anxiety, and suicidality showed significant time\u2010by\u2010class interactions; however, within\u2010 and between\u2010class effect sizes were generally small. Resilience did not exhibit differential changes across classes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Depressive symptom classes among youth with depression or suicidality demonstrate distinct clinical and socio\u2010ecological profiles, highlighting meaningful heterogeneity beyond symptom severity alone. Person\u2010centered approaches may improve characterization of adolescent depression and inform more tailored assessment and intervention strategies. Future longitudinal research should examine the stability of these classes and predictors of transitions between symptom classes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.70211","type":"journal-article","created":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T08:18:39Z","timestamp":1785572319000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A latent class analysis of depressive symptoms in youth from the Texas Youth Depression and Suicide Research Network (\n                    <scp>TX<\/scp>\n                    \u2010\n                    <scp>YDSRN<\/scp>\n                    ): Clinical and socio\u2010ecological correlates"],"prefix":"10.1111","author":[{"given":"Rachel","family":"Lee","sequence":"first","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika S.","family":"Trent","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ace A.","family":"Castillo","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"},{"name":"Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and the Department of Psychiatry University of Texas Southwestern Medical Center  Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu","family":"Minhajuddin","sequence":"additional","affiliation":[{"name":"Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and the Department of Psychiatry University of Texas Southwestern Medical Center  Dallas TX USA"},{"name":"Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center  Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Blader","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Joe R. and Teresa Lozano Long School of Medicine, University of Texas at San Antonio  San Antonio TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar A.","family":"Soutullo","sequence":"additional","affiliation":[{"name":"The University of Texas Health (UTHealth) Houston, Louis A. Faillace Department of Psychiatry and Behavioral Sciences  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Baughn","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of Texas Medical Branch  Galveston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadeel","family":"Hamdan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences University of Texas Medical Branch  Galveston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirti","family":"Saxena","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel A.","family":"Walker","sequence":"additional","affiliation":[{"name":"Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and the Department of Psychiatry University of Texas Southwestern Medical Center  Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynnel C.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and the Department of Psychiatry University of Texas Southwestern Medical Center  Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Wakefield","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Texas Tech University Health Science Center  Lubbock TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne K.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Menninger Department of Psychiatry and Behavioral Sciences Baylor College of Medicine  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhukar 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