{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:04:56Z","timestamp":1789657496683,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005275","name":"Region Hovedstaden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005275","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020584","name":"Region Hovedstadens Psykiatri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020584","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Danmarks Frie Forskningsfond","doi-asserted-by":"publisher","award":["2096\u201000065B"],"award-info":[{"award-number":["2096\u201000065B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","award":["ECSA\u20102020\u2010005"],"award-info":[{"award-number":["ECSA\u20102020\u2010005"]}],"id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Identification of individuals at elevated risk of schizophrenia spectrum and bipolar disorders is a clinical research priority. Current strategies for psychosis risk identification, however, identify only a small proportion of future cases. Additional high\u2010risk approaches are needed, ideally with higher sensitivity, which may include focusing on systems in which risk factors for psychosis are naturally concentrated, such as child and adolescent mental health services (CAMHS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We examined the proportion of psychosis and bipolar disorder cases occurring in individuals who had attended CAMHS. The nationwide Danish population born from 1990 to 2020 was followed from 1995 until 2021 using Danish national health registers to retrieve information on contact with CAMHS and diagnoses of the full spectrum of psychotic and bipolar disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We followed 1,978,630 individuals for 30,855,257 person\u2010years. Of all diagnoses of psychotic or bipolar disorders in the total population by the end of follow\u2010up, 58.3% occurred among individuals who had attended CAMHS. There was an increased risk of all diagnostic outcomes in CAMHS attendees (HR 15.5; 95% CI 15.5\u201315.9 for any psychosis or bipolar disorder). The highest risk was in individuals who had an inpatient psychiatric admission in adolescence (HR 46.8, 95% CI 44.8\u201348.9) where 50% had received a diagnosis of psychosis or bipolar disorder by age 32.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A large proportion of psychotic and bipolar disorder diagnoses in the population occur in individuals who have attended CAMHS. Adolescent CAMHS inpatients are at particularly high risk. These findings highlight CAMHS as a high\u2010capacity, high\u2010risk system for the detection of psychosis and bipolar risk and suggest important potential for large\u2010scale prediction and prevention within CAMHS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.70232","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T14:06:31Z","timestamp":1789653991000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychotic and bipolar disorder diagnoses following contact with child and adolescent mental health services\u2014a longitudinal, nationwide register study of 2 million individuals"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6510-1449","authenticated-orcid":false,"given":"Maja","family":"Gregersen","sequence":"first","affiliation":[{"name":"Child and Adolescent Mental Health Center Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Hjorth\u00f8j","sequence":"additional","affiliation":[{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Department of Public Health, Section of Epidemiology University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Richardt","family":"M\u00f8llegaard Jepsen","sequence":"additional","affiliation":[{"name":"Child and Adolescent Mental Health Center Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Center for Neuropsychiatric Schizophrenia Research and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Erlangsen","sequence":"additional","affiliation":[{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Danish Research Institute for Suicide Prevention Mental Health Centre Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merete","family":"Nordentoft","sequence":"additional","affiliation":[{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Amalie Elgaard","family":"Thorup","sequence":"additional","affiliation":[{"name":"Child and Adolescent Mental Health Center Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1339-9981","authenticated-orcid":false,"given":"Nicoline","family":"Hemager","sequence":"additional","affiliation":[{"name":"Child and Adolescent Mental Health Center Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"CORE, Copenhagen University Hospital \u2010 Bispebjerg and Frederiksberg, Capital Region of Denmark  Copenhagen Denmark"},{"name":"Department of Psychology, Faculty of Social Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1484-651X","authenticated-orcid":false,"given":"Ian","family":"Kelleher","sequence":"additional","affiliation":[{"name":"Institute for Neuroscience and Cardiovascular Research University of Edinburgh  Edinburgh UK"},{"name":"School of Medicine University College Dublin  Dublin Ireland"},{"name":"Faculty of Medicine University of Oulu  Oulu Finland"},{"name":"St John of God Hospitaller Services Group  Dublin 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