{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:17:57Z","timestamp":1793146677180,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,9]],"date-time":"2020-08-09T00:00:00Z","timestamp":1596931200000},"content-version":"am","delay-in-days":365,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T00:00:00Z","timestamp":1565395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T00:00:00Z","timestamp":1565395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP16K09084"],"award-info":[{"award-number":["JP16K09084"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clin Pharm Ther"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1111\/jcpt.13024","type":"journal-article","created":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T18:09:40Z","timestamp":1565460580000},"page":"65-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":122,"title":["Time\u2010to\u2010onset analysis of amiodarone\u2010associated thyroid dysfunction"],"prefix":"10.1155","volume":"45","author":[{"given":"Sayoko","family":"Kinoshita","sequence":"first","affiliation":[{"name":"Ebisu Pharmacy Osaka\u2010shi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichi","family":"Hosomi","sequence":"additional","affiliation":[{"name":"Division of Clinical Drug Informatics, School of Pharmacy Kindai University Higashi\u2010osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Division of Clinical Drug Informatics, School of Pharmacy Kindai University Higashi\u2010osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0834-1005","authenticated-orcid":false,"given":"Mitsutaka","family":"Takada","sequence":"additional","affiliation":[{"name":"Division of Clinical Drug Informatics, School of Pharmacy Kindai University Higashi\u2010osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-013-0410-2"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00220-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.2.149"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1995.tb04072.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-126-1-199701010-00009"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(89)90648-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.134.5.8156930"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2009.225"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.11.1312"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-62-3-563"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2000.107047"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90187-3"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5603\/EP.2015.0025"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(76)90807-9"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198109033051002"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90187-3"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.65.958"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04087.x"},{"issue":"6","key":"e_1_2_7_20_1","first-page":"434","article-title":"Amiodarone\u2010induced thyroid dysfunction in the Hong Kong Chinese population","volume":"16","author":"Lee KF","year":"2010","journal-title":"Hong Kong Med J"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90336-5"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-102-3-412_1"},{"issue":"1","key":"e_1_2_7_23_1","first-page":"2","article-title":"Amiodarone\u2010induced thyroid dysfunction in an iodine\u2010replete area: epidemiological and clinical data","volume":"63","author":"Zosin I","year":"2012","journal-title":"Endokrynol Pol"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.22.2.240"},{"issue":"3","key":"e_1_2_7_25_1","first-page":"340","article-title":"Amiodarone and the thyroid: a 2012 update","volume":"35","author":"Bogazzi F","year":"2012","journal-title":"J Endocrinol Invest"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-013-9910-9"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1987.tb00781.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-101-1-28"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1159\/000180696"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg158"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27302005000600010"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.02.015"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.2298\/MPNS1112533A"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420230115013"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.735"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-013-0061-7"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40780-015-0035-2"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1742"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.771"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100258"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.668"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002280050466"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40780-016-0048-5"},{"issue":"6","key":"e_1_2_7_44_1","first-page":"978","article-title":"Evidence for CYP3A\u2010mediated N\u2010deethylation of amiodarone in human liver microsomal fractions","volume":"21","author":"Fabre G","year":"1993","journal-title":"Drug Metab Dispos"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(83)90006-6"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-017-2195-5"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40261-017-0582-4"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-14-0267"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2009.07.001"}],"container-title":["Journal of Clinical Pharmacy and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpt.13024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jcpt.13024","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpt.13024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T18:04:40Z","timestamp":1671818680000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpt.13024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,10]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/jcpt.13024"],"URL":"https:\/\/doi.org\/10.1111\/jcpt.13024","archive":["Portico"],"relation":{},"ISSN":["0269-4727","1365-2710"],"issn-type":[{"value":"0269-4727","type":"print"},{"value":"1365-2710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,10]]},"assertion":[{"value":"2019-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}