{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T07:06:57Z","timestamp":1765609617129,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,28]],"date-time":"2014-03-28T00:00:00Z","timestamp":1395964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"DOI":"10.13039\/100004358","name":"Samsung Electronics","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004358","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>We sought to determine the association between change in fasting plasma glucose (<jats:styled-content style=\"fixed-case\">FPG<\/jats:styled-content>) and levels of liver enzymes, such as aspartate transaminase, alanine transaminase and gamma\u2010glutamyltransferase, from health examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 9,393 health screen examinees with no evidence of viral hepatitis, liver diseases, abnormal liver function and diabetes in their past disease history were enrolled in the present study. All the participants underwent three health examinations. Group\u00a01 and 4 were stationary groups of those with normal liver enzyme levels in the first and second health examinations (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>1), and abnormal liver enzyme levels in the first and second health check\u2010up (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>4). Groups\u00a02 and 3 were altered groups of those with abnormal liver enzyme levels in the first health examination, which became normal in the second health examination (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>2), and from a normal liver enzymes level to an abnormal liver enzymes level (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">FPG<\/jats:styled-content> levels were elevated in male participants (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01), and were related to old age (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01), drinking (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01), smoking (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01) and so on. There was a strong relationship between <jats:styled-content style=\"fixed-case\">FPG<\/jats:styled-content> levels in the last health examination and altered liver function enzyme levels from the first health examination to the second check\u2010up. In other words, group\u00a04 had the highest level of <jats:styled-content style=\"fixed-case\">FPG<\/jats:styled-content> compared with the other groups (<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>1\u00a0&lt;\u00a0<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>2\u00a0&lt;\u00a0<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>An association was observed between <jats:styled-content style=\"fixed-case\">FPG<\/jats:styled-content> levels and abnormal liver function in manufacturing workers. Abnormal liver function can be closely associated with the development of diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.12202","type":"journal-article","created":{"date-parts":[[2014,3,28]],"date-time":"2014-03-28T20:34:53Z","timestamp":1396038893000},"page":"671-676","source":"Crossref","is-referenced-by-count":7,"title":["Increasing risk of diabetes mellitus according to liver function alterations in electronic workers"],"prefix":"10.1111","volume":"5","author":[{"given":"Kyoungho","family":"Lee","sequence":"first","affiliation":[{"name":"Samsung Health Research Institute Samsung Electronics Yongin\u2010City Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joohee","family":"Han","sequence":"additional","affiliation":[{"name":"Samsung Health Research Institute Samsung Electronics Yongin\u2010City Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo\u2010Geun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Occupational Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.16.1.157"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.9.1414"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4093\/jkda.2007.31.4.362"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.8.1844"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.11.3140"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.12.2913"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.51.6.1889"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.7.1757"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-003-1036-5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.079814"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2005.01581.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0505"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1373\/49.8.1358"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.081257"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(02)80111-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0919"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-0106"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.10058"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2000.00259.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00616-1"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2010.01.002"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008484200"}],"container-title":["Journal of Diabetes Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdi.12202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdi.12202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdi.12202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:26:16Z","timestamp":1695540376000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdi.12202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,28]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/jdi.12202"],"URL":"https:\/\/doi.org\/10.1111\/jdi.12202","archive":["Portico"],"relation":{},"ISSN":["2040-1116","2040-1124"],"issn-type":[{"type":"print","value":"2040-1116"},{"type":"electronic","value":"2040-1124"}],"subject":[],"published":{"date-parts":[[2014,3,28]]}}}