{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:14:25Z","timestamp":1760300065230,"version":"3.37.3"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T00:00:00Z","timestamp":1537747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>Medication adherence, which is decreased by a poor understanding of medications, has a close association with blood glucose level in patients with type\u00a02 diabetes. However, a relationship between the understanding of antidiabetic medication and blood glucose level in patients with type\u00a02 diabetes is unclear. Here, we aimed to investigate the relationship between the understanding of antidiabetic medication and blood glucose level in patients with type\u00a02 diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Lifestyle factors were evaluated by a questionnaire method, in the present cross\u2010sectional study. Poor understanding of antidiabetic medication (<jats:styled-content style=\"fixed-case\">PUAD<\/jats:styled-content>) was defined as a discrepancy between the answer and the actual use of oral antidiabetic medication on the questionnaire. Poor blood glucose level was defined as hemoglobin A1c \u22658%. To investigate the impact of <jats:styled-content style=\"fixed-case\">PUAD<\/jats:styled-content> on poor blood glucose level, propensity\u2010score matching analysis was used to remove the bias of confounding variables, including sex, age, log (duration of diabetes +1), body mass index, number of oral antidiabetic medications, smoking status, alcohol drinking, exercise, nephropathy, neuropathy, oral antidiabetic medications and insulin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 479 patients, 40 patients (8.4%) were categorized into the <jats:styled-content style=\"fixed-case\">PUAD<\/jats:styled-content> group. The hemoglobin A1c of patients with <jats:styled-content style=\"fixed-case\">PUAD<\/jats:styled-content> was higher than that of patients without (7.5 [1.3] vs 7.2 [0.9]%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.041). In the propensity\u2010matched 74 patients, <jats:styled-content style=\"fixed-case\">PUAD<\/jats:styled-content> was associated with poor blood glucose level (odds ratio 5.45, 95% confidence interval 1.54\u201325.8, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.007) by logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A poor understanding of antidiabetic medication is associated with poor blood glucose level in patients with type\u00a02 diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.12916","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T06:29:54Z","timestamp":1535005794000},"page":"458-465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Understanding of antidiabetic medication is associated with blood glucose in patients with type\u00a02 diabetes: At baseline date of the KAMOGAWA\u2010DM cohort study"],"prefix":"10.1111","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0656-8938","authenticated-orcid":false,"given":"Ryosuke","family":"Sakai","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Ushigome","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto 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