{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:18:31Z","timestamp":1788970711097,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T00:00:00Z","timestamp":1555632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>To evaluate the differences in the results of 75\u2010g oral glucose tolerance tests (<jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content>s) according to gestational age in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In this prospective cohort study, 2,578 pregnant women were divided into three categories based on their gestational age during the 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content>: &lt;14\u00a0weeks\u2019 gestation, 14\u201323\u00a0weeks\u2019 gestation and 24\u201332\u00a0weeks\u2019 gestation. The association between gestational age and the results of the 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content> were evaluated using multivariable analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Early gestational age was associated with high fasting plasma glucose levels at the time of the 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content>, and low corresponding 1\u2010h and 2\u2010h <jats:styled-content style=\"fixed-case\">plasma glucose<\/jats:styled-content> levels. Compared with women with a gestational age of 24\u201332\u00a0weeks, women who had undergone the 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content> at &lt;14\u00a0weeks\u2019 gestation had significantly higher odds of gestational diabetes mellitus diagnosis based on the currently used criteria in Japan (adjusted odds ratio 1.42, 95% confidence interval 1.07\u20131.90).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of the 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content> varied by gestational age. The use of the same 75\u2010g <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content> cut\u2010off values for the diagnosis of <jats:styled-content style=\"fixed-case\">gestational diabetes mellitus<\/jats:styled-content>, regardless of gestational age, might lead to increases in the prevalence of <jats:styled-content style=\"fixed-case\">gestational diabetes mellitus<\/jats:styled-content> diagnosis in Japan.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13044","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T19:47:20Z","timestamp":1553197640000},"page":"1576-1585","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Difference in the prevalence of gestational diabetes mellitus according to gestational age at 75\u2010g oral glucose tolerance test in Japan: The Japan Assessment of Gestational Diabetes Mellitus Screening 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