{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T17:34:22Z","timestamp":1783186462367,"version":"3.54.6"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T00:00:00Z","timestamp":1561593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>To compare pregnancy outcomes between women with gestational diabetes mellitus (GDM) diagnosed early and late in pregnancy in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We examined women diagnosed with GDM in this multi\u2010institutional retrospective study. Women were divided into two groups by gestational age at diagnosis: &lt;24\u00a0weeks of gestation (early group, 14.4\u00a0\u00b1\u00a04.2\u00a0weeks) and \u226524\u00a0weeks of gestation (late group, 29.6\u00a0\u00b1\u00a03.4\u00a0weeks). Dietary counseling with self\u2010monitoring of blood glucose with or without insulin therapy was initiated for both groups. Pregnancy outcomes were compared between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data from 600 early and 881 late group participants from 40 institutions were included. Although pre\u2010pregnancy body mass index was higher in the early group than in the late group, gestational weight gain was lower in the early group. Hypertensive disorders of pregnancy and cesarean section were more prevalent in the early than in the late group (9.3% vs 4.8%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001; 34.2% vs 32.0%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001, respectively). The prevalence of large\u2010for\u2010gestational\u2010age infants was higher in the late than in the early group (24.6% vs 19.7%, respectively, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.025). There was no significant difference in other neonatal adverse outcomes between the groups. Multiple logistic regression analysis showed that early group, nulliparity and pre\u2010pregnancy body mass index were associated with hypertensive disorders of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that maternal complications, including hypertensive disorders of pregnancy and cesarean delivery, were higher in the early group than in the late group. Earlier intervention for GDM might be associated with a reduction in large\u2010for\u2010gestational\u2010age infants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13101","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T14:35:08Z","timestamp":1560522908000},"page":"216-222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Comparison of pregnancy outcomes between women with early\u2010onset and late\u2010onset gestational diabetes in a retrospective multi\u2010institutional study in Japan"],"prefix":"10.1111","volume":"11","author":[{"given":"Tomoka","family":"Usami","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Iwama","sequence":"additional","affiliation":[{"name":"Center for Perinatal Medicine Tohoku University Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimasa","family":"Sagawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Rakuwakai Otowa Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reo","family":"Kawano","sequence":"additional","affiliation":[{"name":"Center for Integrated Medical Research Hiroshima University Hospital Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masako","family":"Waguri","sequence":"additional","affiliation":[{"name":"Department of Maternal Internal Medicine Osaka Medical Center and Research Institute for Maternal and Children Health Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Sameshima","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyazaki University School of Medicine Miyazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Hiramatsu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Okayama City General Medical Center Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3715-0075","authenticated-orcid":false,"given":"Takashi","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ehime University Graduate School of Medicine Toon Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Japan Diabetes and Pregnancy Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-s064"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-S002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1790"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.18.1.127"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.11.039"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90371-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0719"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2013.10.020"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ13-0541"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ14-0140"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8227(01)00365-5"},{"key":"e_1_2_7_14_1","first-page":"1271","article-title":"New normative birthweight among Japanese infants according to gestational week at delivery","volume":"114","author":"Itabashi K","year":"2010","journal-title":"Acta Paediatr Jpn"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12419"},{"key":"e_1_2_7_16_1","unstructured":"National Institute of Health and Nutrition.Summary report from the Scientific Committee of \u201cDietary reference intakes for Japanese\u201d. 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