{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T15:55:17Z","timestamp":1772207717988,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>Vitamin\u00a0D levels are negatively correlated with prediabetes risk and hemoglobin A1c levels in individuals with prediabetes. The data are, however, scarce and inconsistent among different populations. We aimed to assess the association of vitamin\u00a0D with prediabetes risk and hemoglobin A1c levels in young Saudi women with normoglycemia and prediabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We analyzed the data of individuals without diabetes (without diabetes history and hemoglobin A1c &lt;6.4%) from the Princess Nourah bint Abdulrahman University\u2019s non\u2010communicable diseases student registry. Demographic data, anthropometric and blood pressure measurements, and hemoglobin A1c and vitamin\u00a0D results were retrieved and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 345 participants were included in the analysis. The prediabetes status showed no association with vitamin\u00a0D levels, but it was significantly associated with the participants\u2019 weight and body mass index. Additionally, there was no correlation between the levels of vitamin\u00a0D and hemoglobin A1c across the whole population, even after correction for body mass index. However, in the body mass index subgroups, when individuals with potentially harmful levels of vitamin\u00a0D (&gt;125\u00a0nmol\/L) were excluded, a positive association was detected between vitamin\u00a0D and hemoglobin A1c levels in the underweight individuals. Hemoglobin A1c values showed a positive correlation only with bodyweight and body mass index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Vitamin\u00a0D levels did not predict prediabetes status and showed no correlation with hemoglobin A1c levels in this population. Vitamin\u00a0D levels\u2019 effect on the risk of prediabetes might be small compared with other well\u2010established risk factors, such as obesity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13226","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T11:45:14Z","timestamp":1580816714000},"page":"1344-1351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Vitamin\u00a0D levels, prediabetes risk and hemoglobin A1c levels in young non\u2010diabetic Saudi women"],"prefix":"10.1111","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5145-0648","authenticated-orcid":false,"given":"Maha A","family":"Al\u2010Mohaissen","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Cardiology Princess Nourah Bint Abdulrahman University Riyadh Saudi Arabia"},{"name":"Princess Nourah Bint Abdulrahman University Cardiovascular Disease in Women Research Chair Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Health Evaluation and Outcome Sciences Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Faris","family":"Alamri","sequence":"additional","affiliation":[{"name":"Department of Family Medicine King Abdullah bin Abdulaziz University Hospital Princess Nourah bint Abdulrahman University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe1906815"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-019-1201-y"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-1829"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-1203"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-016-2758-x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05-1961"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40200-015-0179-5"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516-3180.2013.7180005"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v6.i8.1057"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.65.1.51"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.176345"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcte.2017.04.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/351385"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1900906"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-018-0252-4"},{"key":"e_1_2_7_17_1","first-page":"722","article-title":"Prevalence and future prediction of type 2 diabetes mellitus in the Kingdom of Saudi Arabia: a systematic review of published studies","volume":"66","author":"Meo SA","year":"2016","journal-title":"J Pak Med Assoc"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jegh.2017.10.001"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/jfcm.JFCM_73_17","article-title":"Vitamin D deficiency in Saudi Arabians: a reality or simply hype: a meta\u2010analysis (2008\u20132015)","volume":"25","author":"Al\u2010Alyani H","year":"2018","journal-title":"J Family Community Med"},{"key":"e_1_2_7_20_1","first-page":"814","article-title":"Prevalence of vitamin D deficiency in Saudi adults","volume":"34","author":"Alsuwadia AO","year":"2013","journal-title":"Saudi Med J"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1179562X17702391"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-019-1107-y"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-S081"},{"key":"e_1_2_7_24_1","unstructured":"Vitamin D Status: United States 2001\u20132006.2015. 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