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Status of diabetes, comorbidities, complications and treatments were ascertained through data linkage to Taiwan\u2019s National Health Insurance Research Database. Multivariable ordinary least squares, Tobit and median regression analyses were used to estimate the coefficients that represented independent impacts of patients\u2019 characteristics on health\u2010related quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean health utility score for 2,104 participants was 0.838. Being female, aging, divorced\/widowed, never worked or underweight, or having a lower monthly household income, injectable glucose\u2010lowering therapy, comorbid connective tissue disease or depression were associated with lower health utilities. Having an amputation led to the largest reduction by 0.288 in health utilities, followed by debilitating stroke (0.266), heart failure (0.237), other coronary heart disease (0.185), kidney dialysis\/transplant (0.148), coronary revascularizations (0.093), transient ischemic attack\/stroke (0.078), diabetic neuropathy (0.062), polyneuropathy (0.055) and other neuropathy (0.043).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Major vascular complications, connective tissue disease and depression are associated with considerably worse health\u2010related quality of life. These health utility estimates can facilitate health economic evaluations to determine cost\u2010effective strategies for diabetes management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13520","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T08:06:08Z","timestamp":1612598768000},"page":"1749-1758","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Valuing health states of people with type\u00a02 diabetes: Analyses of the nationwide representative linked databases"],"prefix":"10.1111","volume":"12","author":[{"given":"Shihchen","family":"Kuo","sequence":"first","affiliation":[{"name":"Division of Metabolism, Endocrinology &amp; Diabetes Department of Internal Medicine University of Michigan Medical School Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Ting","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Clinical Pharmacy and Pharmaceutical Sciences College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsuan\u2010Ying","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Pharmacy and Pharmaceutical Sciences College of Medicine National Cheng Kung University Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5475-7848","authenticated-orcid":false,"given":"Huang\u2010Tz","family":"Ou","sequence":"additional","affiliation":[{"name":"Institute of Clinical Pharmacy and Pharmaceutical Sciences College of Medicine National Cheng Kung University Tainan Taiwan"},{"name":"Department of Pharmacy College of Medicine National Cheng Kung University Tainan Taiwan"},{"name":"Department of Pharmacy National Cheng Kung University Hospital Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-S005"},{"key":"e_1_2_7_3_1","unstructured":"Assessing cost effectiveness. 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