{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T19:09:48Z","timestamp":1776539388256,"version":"3.51.2"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T00:00:00Z","timestamp":1620345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>This study aimed to reveal lifestyle changes and their impact on glycemic control and weight control in patients with diabetes during the coronavirus disease 2019 (COVID\u201019) pandemic in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We retrospectively analyzed 1,402 outpatients with diabetes at a clinic in Osaka, Japan, who responded to an interview sheet regarding lifestyle changes during the COVID\u201019 pandemic between 28 March and 30 May 2020. The association of lifestyle changes with hemoglobin A1c (HbA1c) and weight changes from February to May 2020 was investigated using the linear regression model. We also investigated the association with clinically important change of HbA1c (by \u22650.3%) and bodyweight (by \u22653%), using the cumulative link model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Leisure time and other outside physical activities were decreased in one\u2010quarter of patients during the COVID\u201019 pandemic, whereas the amount of meals and snacks was decreased and increased in approximately 10%, respectively. The change in leisure time physical activities was inversely associated with HbA1c and weight changes, whereas the quantitative change of meals with the decline in eating out and that of snacks were positively associated with HbA1c and weight changes (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The quantitative change of meals without the decline in eating out was also positively associated with weight change (<jats:italic>P<\/jats:italic>\u2009=\u20090.012). The cumulative link model for clinically important HbA1c and weight change showed broadly similar associations, except for that between snacks and bodyweight (<jats:italic>P<\/jats:italic>\u2009=\u20090.15).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A considerable number of outpatients with diabetes experienced lifestyle changes during the COVID\u201019 pandemic. The lifestyle changes were associated with HbA1c and weight changes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13555","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T08:05:02Z","timestamp":1616745902000},"page":"375-385","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Lifestyle changes and their impact on glycemic control and weight control in patients with diabetes during the coronavirus disease 2019 pandemic in Japan"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5105-041X","authenticated-orcid":false,"given":"Mitsuyoshi","family":"Takahara","sequence":"first","affiliation":[{"name":"Department of Diabetes Care Medicine Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotaka","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Metabolic Medicine Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Shiraiwa","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Maeno","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Shiraiwa","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norio","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Shiraiwa Medical Clinic Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9020-8320","authenticated-orcid":false,"given":"Naoto","family":"Katakami","sequence":"additional","affiliation":[{"name":"Department of Metabolic Medicine Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iichiro","family":"Shimomura","sequence":"additional","affiliation":[{"name":"Department of Metabolic Medicine Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,7]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Japan's Ministry of Health L and Welfare.Press Conference on COVID\u201019. Available from:https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/newpage_00032.htmlAccessed October 17 2020."},{"key":"e_1_2_7_3_1","unstructured":"Secretariat JGsC.COVID\u201019 Information and Resources. Available from:https:\/\/corona.go.jp\/en\/Accessed October 17 2020."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13340-020-00439-5"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.13306"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ20-0426"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13340-020-00467-1"},{"key":"e_1_2_7_8_1","unstructured":"European Medicines Agency.Clinical investigation of medicinal products in the treatment or prevention of diabetes mellitus. Available from:https:\/\/www.ema.europa.eu\/en\/clinical\u2010investigation\u2010medicinal\u2010products\u2010treatment\u2010prevention\u2010diabetes\u2010mellitusAccessed October 17 2020."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2014.10.018"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.orcp.2013.10.003"},{"key":"e_1_2_7_11_1","volume-title":"Guidelines for the Management of Obesity Disease 2016","author":"The Japan Society for the Study of Obesity","year":"2016"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-3991(98)00013-5"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2012.06.028"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2015.00369"},{"issue":"1","key":"e_1_2_7_15_1","first-page":"S106","article-title":"Tests of glycemia in diabetes","volume":"26","author":"Goldstein DE","year":"2003","journal-title":"Diabetes Care"}],"container-title":["Journal of Diabetes Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdi.13555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jdi.13555","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdi.13555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T08:05:10Z","timestamp":1693123510000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdi.13555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,7]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1111\/jdi.13555"],"URL":"https:\/\/doi.org\/10.1111\/jdi.13555","archive":["Portico"],"relation":{},"ISSN":["2040-1116","2040-1124"],"issn-type":[{"value":"2040-1116","type":"print"},{"value":"2040-1124","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,7]]},"assertion":[{"value":"2020-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}