{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T05:48:25Z","timestamp":1771652905210,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T00:00:00Z","timestamp":1630368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>We aimed to determine the hospital\u2010based prevalence and clinical features of fulminant type\u20091 diabetes mellitus in Korea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We identified all patients with diabetes who regularly visited the Endocrinology outpatient clinics at eight centers for a period &gt;1\u2009year between January 2012 and June 2017. We investigated their medical records retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During this period, 76,309 patients with diabetes had been regularly followed up. Among them, 913 (1.2%) patients had type\u20091 diabetes mellitus . There were 462 patients with type\u20091 diabetes mellitus whose data at the time of the first diagnosis could be identified (359 and 103 with non\u2010ketosis and ketosis onset, respectively). Of these, 15 (3.2% of type\u20091 diabetes mellitus, 14.6% of ketosis onset diabetes) patients had fulminant type\u20091 diabetes mellitus. The median ages at diagnosis were 40 and 27\u2009years in the fulminant type\u20091 diabetes mellitus and non\u2010fulminant type\u20091 diabetes mellitus groups, respectively. The patients with fulminant type\u20091 diabetes mellitus had higher body mass index, lower glycated hemoglobin and fasting\/peak C\u2010peptide, and lower frequent glutamic acid decarboxylase antibody\u2010positive rate (<jats:italic>P\u2009<\/jats:italic>=0.0010) at diagnosis. Furthermore, they had lower glycated hemoglobin at the last follow\u2010up examination than those with non\u2010fulminant type\u20091 diabetes mellitus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this study, the prevalence of type\u20091 diabetes mellitus was 1.2% among all patients with diabetes, and that of fulminant type\u20091 diabetes mellitus was 3.2% among those newly diagnosed with type\u20091 diabetes mellitus. The glycated hemoglobin levels were lower in patients with fulminant type\u20091 diabetes mellitus than in those with non\u2010fulminant type\u20091 diabetes mellitus at diagnosis and at the last follow\u2010up examination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.13638","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T07:56:35Z","timestamp":1627372595000},"page":"47-53","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prevalence and clinical characteristics of fulminant type\u20091 diabetes mellitus in Korean adults: A multi\u2010institutional joint research"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4829-3407","authenticated-orcid":false,"given":"Sun Ok","family":"Song","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine National Health Insurance Service Ilsan Hospital Goyang Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae\u2010Seung","family":"Yun","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine St. Vincent's Hospital The Catholic University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3703-1479","authenticated-orcid":false,"given":"Seung\u2010Hyun","family":"Ko","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine St. Vincent's Hospital The Catholic University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Bae","family":"Ahn","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine St. Vincent's Hospital The Catholic University College of Medicine Seoul 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Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1025-2044","authenticated-orcid":false,"given":"Dae Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Ajou University School of Medicine Suwon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da Hae","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Inha University Hospital Inha University School of Medicine Incheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2554-3664","authenticated-orcid":false,"given":"So Hun","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Inha University Hospital Inha University School of Medicine Incheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Hyun","family":"Noh","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine Inje University Ilsan Paik Hospital Inje University College of Medicine Goyang Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine Korea University Ansan Hospital Korea University College of Medicine Ansan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7738-2284","authenticated-orcid":false,"given":"Kyung\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine CHA Bundang Medical Center CHA University Seongnam 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