{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:58:00Z","timestamp":1791917880892,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T00:00:00Z","timestamp":1651708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011680","name":"King Fahad Medical City","doi-asserted-by":"publisher","award":["17\u2010057"],"award-info":[{"award-number":["17\u2010057"]}],"id":[{"id":"10.13039\/501100011680","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["BMRP\u20105726113101"],"award-info":[{"award-number":["BMRP\u20105726113101"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims\/Introduction<\/jats:title>\n                    <jats:p>This study determined the prevalence and risk factors for diabetic peripheral neuropathy (DPN), painful DPN and diabetic foot ulceration (DFU) in patients with type\u20092 diabetes in secondary healthcare in Qatar, Kuwait and the Kingdom of Saudi Arabia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Adults aged 18\u201385\u2009years with type\u20092 diabetes were randomly enrolled from secondary healthcare, and underwent clinical and metabolic assessment. DPN was evaluated using vibration perception threshold and neuropathic symptoms and painful Diabetic Peripheral Neuropathy was evaluated using the Douleur Neuropathique 4 questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 3,021 individuals were recruited between June 2017 and May 2019. The prevalence of DPN was 33.3%, of whom 52.2% were at risk of DFU and 53.6% were undiagnosed. The prevalence of painful DPN was 43.3%, of whom 54.3% were undiagnosed. DFU was present in 2.9%. The adjusted odds ratios for DPN and painful DPN were higher with increasing diabetes duration, obesity, poor glycemic control and hyperlipidemia, and lower with greater physical activity. The adjusted odds ratio for DFU was higher with the presence of DPN, severe loss of vibration perception, hypertension and vitamin\u2009D deficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the largest study to date from the Middle East showing a high prevalence of undiagnosed DPN, painful DPN and those at risk of DFU in patients with type\u20092 diabetes, and identifies their respective risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdi.13815","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T23:54:50Z","timestamp":1650498890000},"page":"1551-1559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Prevalence and risk factors for diabetic peripheral neuropathy, neuropathic pain and foot ulceration in the Arabian Gulf region"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-1248","authenticated-orcid":false,"given":"Georgios","family":"Ponirakis","sequence":"first","affiliation":[{"name":"Department of Medicine Weill Cornell Medicine\u2010Qatar, Qatar Foundation Education City Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik","family":"Elhadd","sequence":"additional","affiliation":[{"name":"National Diabetes Center Hamad General Hospital, Hamad Medical Corporation Doha Qatar"},{"name":"National Diabetes Center Al\u2010Wakra Hospital, Hamad Medical Corporation Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5006-4369","authenticated-orcid":false,"given":"Ebaa","family":"Al Ozairi","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Dasman Diabetes Institute Kuwait City Kuwait"},{"name":"Department of Medicine Kuwait University Kuwait City 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