{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:08:14Z","timestamp":1784956094472,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:00:00Z","timestamp":1699315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims\/Introduction<\/jats:title><jats:p>This study evaluated the effects of the Medtronic MiniMed 770G hybrid closed\u2010loop system on glycemic control and psychological aspects in persons with type\u20091 diabetes mellitus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This 3\u2010month prospective observational study included 22 participants with type\u20091 diabetes mellitus who used the Medtronic MiniMed 640G predictive low\u2010glucose suspend system and were switched to the 770G system. Time in the range of 70\u2013180\u2009mg\/dL and glycated hemoglobin levels were evaluated; satisfaction, emotional distress and quality of life were assessed using self\u2010reported questionnaires, including the Diabetes Treatment Satisfaction Questionnaire Status, Problem Area in Diabetes and Diabetes Therapy\u2010Related Quality of Life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Time in the range of 70\u2013180\u2009mg\/dL increased (63.5\u2009\u00b1\u200913.4 to 73.0\u2009\u00b1\u200910.9% [mean\u2009\u00b1\u2009standard deviation], <jats:italic>P<\/jats:italic>\u2009=\u20090.0010), and time above the range of 181\u2013250\u2009mg\/dL decreased (26.9\u2009\u00b1\u20098.9 to 19.6\u2009\u00b1\u20097.1%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0005). Glycated hemoglobin levels decreased (7.7\u2009\u00b1\u20091.0 to 7.2\u2009\u00b1\u20090.8%, <jats:italic>P<\/jats:italic>\u2009=\u20090.0021). The percentage of participants with time below the range of 54\u201369\u2009mg\/dL &lt;4% of readings increased from 91% to 100% (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0005). No significant changes were detected in the satisfaction, emotional distress and quality of life levels, but increased sensor calibration might be related to worsened emotional distress and quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The hybrid closed\u2010loop system decreased hyperglycemia and minimized hypoglycemia, but did not improve psychological aspects compared with the predictive low\u2010glucose suspend system, probably because sensor calibration was increased.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdi.14103","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T14:59:55Z","timestamp":1699369195000},"page":"219-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of hybrid closed\u2010loop system on glycemic control and psychological aspects in persons with type\u20091 diabetes treated with sensor\u2010augmented pump: A prospective single\u2010center observational study"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9942-9661","authenticated-orcid":false,"given":"Tomoaki","family":"Akiyama","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Diabetes Yokohama City University Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6329-0939","authenticated-orcid":false,"given":"Tadashi","family":"Yamakawa","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Diabetes Yokohama City University Medical Center  Yokohama Japan"},{"name":"Kanazawa Medical Clinic  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Orime","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Diabetes Yokohama City University Medical Center  Yokohama 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