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All of the following three criteria must be met for \u2018a definitive diagnosis of SPIDDM\u2019: (1) presence of anti\u2010islet autoantibodies at some point in time during the disease course; (2) absence of ketosis or ketoacidosis at the diagnosis of diabetes with no requirement for insulin treatment to correct hyperglycemia immediately after diagnosis in principle; and (3) gradual decrease of insulin secretion over time, with insulin treatment required at more than 3\u2009months after diagnosis, and the presence of severe endogenous insulin deficiency (fasting serum C\u2010peptide immunoreactivity &lt;0.6\u2009ng\/mL) at the last observed point in time. When a patient fulfills only (1) and (2), but not (3), he\/she is diagnosed with \u2018SPIDDM (probable)\u2019 because\u00a0the diabetes is non\u2010insulin\u2010dependent type.<\/jats:p>","DOI":"10.1111\/jdi.14121","type":"journal-article","created":{"date-parts":[[2024,1,7]],"date-time":"2024-01-07T16:20:31Z","timestamp":1704644431000},"page":"254-257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version)"],"prefix":"10.1111","volume":"15","author":[{"given":"Akira","family":"Shimada","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Diabetes, School of Medicine Saitama Medical University  Saitama 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