{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T12:10:01Z","timestamp":1756728601318,"version":"3.44.0"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Malignant hyperthermia (MH) is a rare but life\u2010threatening disorder induced by volatile anesthetics or depolarizing muscle relaxants. Studies have reported the increased prevalence of hyperglycemia among patients susceptible to MH. Herein, we present the case of a 13\u2010month\u2010old toddler who had successfully undergone dextro\u2010transposition of the great arteries and required main and bilateral pulmonary artery augmentation because of residual pulmonary atresia. The patient exhibited atypical manifestations of MH including hyperglycemia with an inadequate insulin response during the perioperative period. The hyperglycemia resolved following administration of dantrolene, the antidote for MH. Research has associated intracellular calcium leaks with reduced glucose storage in human muscle. Metabolic alterations in patients susceptible to MH may predispose them to hyperglycemia during acute MH episodes.<\/jats:p>","DOI":"10.1111\/jdi.70120","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T10:13:11Z","timestamp":1751537591000},"page":"1767-1770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hyperglycemia as an atypical finding of malignant hyperthermia: A case report and literature review"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1456-5366","authenticated-orcid":false,"given":"Huai\u2010Jhih","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Anesthesia Taichung Armed Forces General Hospital  Taichung Taiwan, R.O.C."},{"name":"National Defense Medical Center  Taipei Taiwan, R.O.C."},{"name":"Department of Anesthesia Kaohsiung Veterans General Hospital  Kaohsiung Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010Yi","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Kaohsiung Veterans General Hospital  Kaohsiung Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung\u2010Yun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Kaohsiung Veterans General Hospital  Kaohsiung Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010Chen","family":"Sun","sequence":"additional","affiliation":[{"name":"National Defense Medical Center  Taipei Taiwan, R.O.C."},{"name":"Department of Anesthesia Kaohsiung Veterans General Hospital  Kaohsiung Taiwan, R.O.C."},{"name":"Department of Anesthesia Taoyuan Armed Forces General Hospital  Taoyuan Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-6377","authenticated-orcid":false,"given":"Chun\u2010Hsien","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Anesthesia Kaohsiung Veterans General Hospital  Kaohsiung Taiwan, R.O.C."},{"name":"Department of Nursing Meiho University  Pingtung Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15317"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-21"},{"key":"e_1_2_6_4_1","first-page":"700","article-title":"Incidence of malignant hyperthermia in Denmark","volume":"64","author":"Ording H","year":"1985","journal-title":"Anesth Analg"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199404000-00008"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.09.014"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.53999"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182a8fad0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13221888"}],"container-title":["Journal of Diabetes Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdi.70120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T11:54:38Z","timestamp":1756727678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdi.70120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,3]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/jdi.70120"],"URL":"https:\/\/doi.org\/10.1111\/jdi.70120","archive":["Portico"],"relation":{},"ISSN":["2040-1116","2040-1124"],"issn-type":[{"type":"print","value":"2040-1116"},{"type":"electronic","value":"2040-1124"}],"subject":[],"published":{"date-parts":[[2025,7,3]]},"assertion":[{"value":"2025-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}