{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T16:26:35Z","timestamp":1775060795002,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The escalating burden of type 1 diabetes\u2010related chronic kidney disease (CKD\u2010T1DM) presents a critical public health challenge worldwide. This study aims to comprehensively evaluate the longitudinal trends in disease burden and healthcare quality for CKD\u2010T1DM in East Asia compared with global patterns from 1990 to 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Utilizing data from the Global Burden of Disease (GBD) Study 2023, we analyzed the age\u2010standardized incidence (ASIR), mortality (ASMR), and disability\u2010adjusted life years (ASDR) rates of CKD\u2010T1DM. The Estimated Annual Percentage Change (EAPC) was calculated to quantify temporal trends. Additionally, a multidimensional quality of care index (QCI) was constructed using principal component analysis (PCA) based on four proxy indicators to assess and benchmark healthcare performance across East Asian countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Contrary to the global trend of rising mortality and disability burdens, East Asia exhibited a significant concurrent decline in ASIR, ASMR, and ASDR from 1990 to 2023. However, substantial regional heterogeneity was observed: Japan and South Korea maintained consistently high QCI scores (63.8\u201375.0), while China, Mongolia, and North Korea lagged significantly behind. The study also confirmed a bimodal age\u2010specific incidence pattern peaking in adolescence (10\u201314\u2009years) and older adulthood (55\u201369\u2009years), alongside notable gender disparities in older populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>East Asia has achieved remarkable progress in mitigating the CKD\u2010T1DM burden, diverging significantly from the global trajectory; however, deep structural inequities in care quality persist between high\u2010income and middle\u2010to\u2010low\u2010income nations. Integrating QCI into national monitoring systems and prioritizing comprehensive, lifespan\u2010oriented management strategies are essential to addressing these disparities and sustaining regional improvements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdi.70259","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:56:03Z","timestamp":1770976563000},"page":"649-662","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tracking three decades of type 1 diabetes\u2010related chronic kidney disease in East Asia: Burden, age\u2013sex patterns, and quality of care index"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0320-4137","authenticated-orcid":false,"given":"Qiongfang","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital of Army Medical University  Chongqing 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