{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:30:47Z","timestamp":1777951847175,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A 61\u2010year\u2010old man visited our hospital with a sudden onset of polydipsia and polyuria occurring 5\u2009days prior, accompanied by a 5\u2010kg weight loss. A month prior, his glycated hemoglobin level was 6.2%. Precisely 8\u2009days before the first visit, he had a fever, and hyperglycemic symptoms began shortly thereafter. At the first visit, he had a blood glucose level of 465\u2009mg\/dL, a glycated hemoglobin level of 7.7%, and ketosis. He was diagnosed with fulminant type 1 diabetes mellitus. The antiglutamic acid decarboxylase (GAD) antibodies were &gt;2000\u2009IU\/mL, without other pancreatic islet\u2010related autoantibodies. The human leukocyte antigen haplotype was\n                    <jats:italic>DRB1*09:01\u2010DQB1*03:03<\/jats:italic>\n                    and\n                    <jats:italic>DRB1*13:02\u2010DQB1*06:04<\/jats:italic>\n                    . Intensive insulin therapy was initiated, and the patient was admitted for monitoring the blood glucose profile. The anti\u2010GAD antibody turned negative approximately 7\u2009months later. Some infections may have triggered rapid pancreatic islet destruction in an autoimmunity\u2010induced impaired glucose tolerance state.\n                  <\/jats:p>","DOI":"10.1111\/jdi.70260","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:22:50Z","timestamp":1773768170000},"page":"892-896","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fulminant type 1 diabetes with high\u2010titer anti\u2010glutamic acid decarboxylase antibodies: Likely rapid progression from stage 2 to 3"],"prefix":"10.1111","volume":"17","author":[{"given":"Megumi","family":"Sato","sequence":"first","affiliation":[{"name":"Division of Diabetology and Metabolism, Department of Internal Medicine Tokyo Women's Medical University School of Medicine  Shinjuku\u2010ku Tokyo Japan"},{"name":"Division of Endocrinology, Department of Internal Medicine Tokyo Women's Medical University School of Medicine  Shinjuku\u2010ku Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junnosuke","family":"Miura","sequence":"additional","affiliation":[{"name":"Division of Diabetology and Metabolism, Department of Internal Medicine Tokyo Women's Medical University School of Medicine  Shinjuku\u2010ku Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Oyatsu","sequence":"additional","affiliation":[{"name":"Division of Diabetology and Metabolism, Department of Internal Medicine Tokyo Women's Medical University School of Medicine  Shinjuku\u2010ku Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Internal Medicine Tokyo Women's Medical University School of Medicine  Shinjuku\u2010ku Tokyo 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