{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:39:10Z","timestamp":1783021150767,"version":"3.54.6"},"reference-count":21,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Diabetic peripheral neuropathy (DPN) is a severe complication of diabetes mellitus (DM). Measurement of plantar fascia thickness (PFT) by ultrasound has been proposed as an alternative index of tissue glycation and a marker for diabetes complications such as DPN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Design and Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted in 290 patients with type 1 DM (age 54 [20\u201387] years and diabetes duration 28 [1\u201379] years) and 41 healthy volunteers (age 49 [26\u201373] years). PFT was measured during outpatient clinical evaluation by means of ultrasound. Values were compared with sex, age, anthropometric parameters, advanced glycation end products (AGEs) measured by skin autofluorescence, and parameters derived from clinical evaluation of DPN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with type 1 DM had significantly thicker plantar fascia than controls (2.9\u2009\u00b1\u20090.6\u2009mm vs. 2.4\u2009\u00b1\u20090.2\u2009mm;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001); 199\/290 (68.6%) patients with type 1 DM had altered PFT. In this population, male patients and those with worse glycemic control and longer duration of disease had a higher risk of having altered PFT. Higher PFT was significantly associated with reduced vibration sensitivity, higher levels of HbA1c and AGEs, presence of retinopathy and reduced renal function, and a worse diabetic foot risk classification. The use of AHCL integrated systems appeared to be associated with better plantar fascia outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings indicate that PFT showed a relationship with diabetes microvascular complications, glucometabolic compensation, and with the use of automated insulin delivery systems. PFT might be a useful tool in the assessment of patients with T1DM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdi.70310","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:27:48Z","timestamp":1777354068000},"page":"1210-1217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates"],"prefix":"10.1111","volume":"17","author":[{"given":"Giulia","family":"Casadei","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Diabetes Prevention and Care IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6345-2569","authenticated-orcid":false,"given":"Michele","family":"Baldari","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes Prevention and Care IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna  Bologna Italy"},{"name":"Department of Medical and Surgical Sciences (DIMEC) Alma Mater Studiorum University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Brognara","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences\u2010DIBINEM University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Saudelli","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes Prevention and Care IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna  Bologna Italy"},{"name":"Department of Medical and Surgical Sciences (DIMEC) Alma Mater Studiorum University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Moscatiello","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes Prevention and Care IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Flamigni","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes Prevention and Care IRCCS Azienda Ospedaliero\u2010Universitaria di Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Traina","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences\u2010DIBINEM University of Bologna  Bologna Italy"},{"name":"Orthopaedic\u2010Traumatology and Prosthetic Surgery and Revisions of Hip and Knee Implants IRCCS Istituto Ortopedico Rizzoli  Bologna 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University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-021-00697-7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.2832"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2750"},{"key":"e_1_2_10_5_1","first-page":"81","article-title":"Effects of type two diabetes mellitus on the plantar aponeurosis of Nigerians","volume":"5","author":"Udoh BE","year":"2010","journal-title":"World J Med 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