{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T16:13:10Z","timestamp":1788365590945,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Diabetes Invest"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims\/Introduction<\/jats:title>\n                    <jats:p>Sensor\u2010augmented pump (SAP) therapy has evolved sequentially, but long\u2010term clinical evidence supporting these advances has remained limited. We here evaluated the impact of updates to SAP therapy on glycemic outcomes in individuals with type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study (SAP\u2010J T1D) included Japanese individuals with type 1 diabetes receiving SAP therapy. Treatment efficacy of the MiniMed 620G, 640G, and 770G systems (Medtronic) was evaluated at three predefined time points: baseline (before the switch from 620G to 640G), before the switch from 640G to 770G, and 1\u2009year after the switch to 770G. The primary outcome was the change in time in range (TIR) for continuous glucose monitoring from baseline to 1\u2009year after the transition to the MiniMed 770G system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 47 participants were included in the analysis. The median age was 45\u2009years (interquartile range, 33\u201356\u2009years), and the median body mass index was 22.3\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      (20.4\u201323.7\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). TIR increased progressively with each system update, from 69.0% (61.5\u201375.5%) with MiniMed 620G, to 72.0% (63.5\u201379.0%) with MiniMed 640G, and to 77.0% (73.0\u201380.5%) with MiniMed 770G. Time below range decreased after the switch to MiniMed 640G, whereas time above range decreased after that to MiniMed 770G. Time in tight range increased after the transition to the MiniMed 770G system.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sequential updates in SAP therapy were associated with stepwise improvements in glycemic management, reflecting the distinct functional characteristics of each system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdi.70387","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T15:13:27Z","timestamp":1783696407000},"page":"1499-1505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of system updates for sensor\u2010augmented pump therapy on glycemic management in Japanese individuals with type 1 diabetes (\n                    <scp>SAP<\/scp>\n                    \u2010J\n                    <scp>T1D<\/scp>\n                    study)"],"prefix":"10.1111","volume":"17","author":[{"given":"Shuichiro","family":"Saito","sequence":"first","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akane","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoko","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Nakatsuji","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Nishikage","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomofumi","family":"Takayoshi","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0432-4366","authenticated-orcid":false,"given":"Wataru","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Division of Metabolic Diseases, Department of Translational Medical Science Kobe University Graduate School of Medicine  Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3035-4155","authenticated-orcid":false,"given":"Yushi","family":"Hirota","sequence":"additional","affiliation":[{"name":"Division of Diabetes and Endocrinology, 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