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Mechanobullous <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content>, referred to as classic <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content>, presents with skin fragility, blisters and dystrophic changes on trauma\u2010prone areas. Inflammatory <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content> resembles other autoimmune subepidermal bullous diseases. Compelling evidence from mouse models supports a pathogenic role of autoantibodies against type <jats:styled-content style=\"fixed-case\">VII<\/jats:styled-content> collagen in <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content>. Treatment of <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content> is often unsatisfactory. The most widely used systemic treatment is corticosteroids. Colchicine and dapsone have been reported to be good treatment modalities when combined with corticosteroids. Some intractable cases of <jats:styled-content style=\"fixed-case\">EBA<\/jats:styled-content> have successfully been treated with intravenous immunoglobulin or rituximab.<\/jats:p>","DOI":"10.1111\/jdv.12096","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T17:08:36Z","timestamp":1359738516000},"page":"1204-1213","source":"Crossref","is-referenced-by-count":52,"title":["Epidermolysis bullosa acquisita"],"prefix":"10.1111","volume":"27","author":[{"given":"J.H.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Dermatology and Cutaneous Biology Research Institute, Gangnam Severance Hospital, Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u2010C.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Cutaneous Biology Research Institute, Gangnam Severance Hospital, Yonsei University College of Medicine Seoul 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