{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:06:06Z","timestamp":1791932766965,"version":"4.3.4"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Treatment of hookworm\u2010related cutaneous larva migrans (Hr<jats:styled-content style=\"fixed-case\">CLM<\/jats:styled-content>) with a single dose of oral ivermectin has not been adequately evaluated to date. Response rates reported in three large studies varied from 77% to more than 95%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We evaluated the efficacy of ivermectin in the treatment of Hr<jats:styled-content style=\"fixed-case\">CLM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively studied\u00a0all returning travellers with Hr<jats:styled-content style=\"fixed-case\">CLM<\/jats:styled-content> who consulted in our institution. Patients were then treated with a single, 200\u00a0\u03bcg\/kg dose of ivermectin, orally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010two travellers (35 female, 27 male, mean age 35.6\u00a0years) with Hr<jats:styled-content style=\"fixed-case\">CLM<\/jats:styled-content> and creeping dermatitis were included. Six patients (10%) also had associated hookworm folliculitis. Fifty\u2010nine patients (95%) completely responded with one ivermectin dose. The response rate was 98% in the 56 patients presenting with only creeping dermatitis and 66% in the six patients presenting with additional hookworm folliculitis (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The efficacy of a single dose of oral ivermectin is higher in patients with only creeping dermatitis than in those with associated hookworm folliculitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12097","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T17:10:32Z","timestamp":1359738632000},"page":"655-657","source":"Crossref","is-referenced-by-count":34,"title":["The efficacy of single dose ivermectin in the treatment of hookworm related cutaneous larva migrans varies depending on the clinical presentation"],"prefix":"10.1111","volume":"28","author":[{"given":"C.","family":"Vanhaecke","sequence":"first","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Perignon","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Monsel","sequence":"additional","affiliation":[{"name":"Service de Dermatologie, H\u00f4pital Saint Louis Paris Cedex 10 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Regnier","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Bricaire","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Caumes","sequence":"additional","affiliation":[{"name":"Service de Maladies Infectieuses et Tropicales, H\u00f4pital Piti\u00e9 Salp\u00eatri\u00e8re Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2010.01.005"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70098-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8305.2007.00148.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199810223391714"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.3.542"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/313942"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/19.6.1062"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1001\/archderm.1993.01680260058006","article-title":"Creeping Eruption: A Review of Clinical Presentation and Management of 60 Cases Presenting to a Tropical Disease 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