{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:11:11Z","timestamp":1787015471964,"version":"build-2736575974"},"reference-count":4,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,4,26]],"date-time":"2013-04-26T00:00:00Z","timestamp":1366934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Guidelines for the management of genital Lichen sclerosus (\n                      <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>\n                      ) have recently been updated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To look at the audit points suggested by the updated guidelines: performance of biopsies in active\n                      <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>\n                      not responding to treatment; clear follow\u2010up arrangements for patients with active disease; patient awareness of need to report suspicious lesions; and use of an appropriate topical steroid regieme.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Patients with a diagnosis of genital\n                      <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>\n                      seen over the preceding 12\u00a0months were identified from eight hospital Trusts. In this study, 194 patients participated, 178 females and 16 males.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The diagnosis was purely clinical in 62 patients \u2013 the remainder required biopsies. The commonest reason for performing a biopsy was to clarify the diagnosis (116), followed by to rule out malignancy (11). The majority (98%) were offered follow\u2010up after the initial consultation and only 19 patients were discharged to primary care. In this study, 37% patients had documented evidence that a patient information leaflet had been given. 112 were treated with the clobetasol propionate 0.05% regieme quoted in the guideline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      We conclude biopsies should be done as indicated in the guideline and the reason for biopsy documented. Discharge may be possible at 6\u00a0months for stable uncomplicated disease, although this may prove difficult if adequate follow\u2010up arrangements are not available in the community. We advocate that all patients should receive a patient information leaflet and must be made aware of the increased risk of\n                      <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content>\n                      . Topical corticosteroid treatment should be simplied to the regieme documented in the guidelines unless contraindicated.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.12173","type":"journal-article","created":{"date-parts":[[2013,4,26]],"date-time":"2013-04-26T06:42:11Z","timestamp":1366958531000},"page":"963-966","source":"Crossref","is-referenced-by-count":6,"title":["A multi\u2010centre audit on genital Lichen sclerosus in the North West of England"],"prefix":"10.1111","volume":"28","author":[{"given":"G.","family":"Raj","sequence":"first","affiliation":[{"name":"Lanarkshire centre for Dermatology Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. K.","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Dermatology Royal Liverpool and Broadgreen University Hospital Trust Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09997.x"},{"key":"e_1_2_6_3_1","first-page":"1476","volume-title":"Dermatology","author":"Rochen M","year":"2008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.05012.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443610701251539"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12173","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12173","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:54:35Z","timestamp":1695542075000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,26]]},"references-count":4,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/jdv.12173"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12173","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,26]]}}}