{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:45:46Z","timestamp":1758980746394,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"SNFMI-Genzyme-maladies rares"},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique (CNRS)","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Assistance Publique H\u00f4pitaux de Paris (AP-HP)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mastocytosis is a heterogeneous disease whose different subtypes also vary in aggressivity. Children typically present with cutaneous mastocytosis. We identified, in our previous work, a peripheral <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>34\u2010c\u2010Kit+mast cell precursor by flow cytometry in systemic forms but not in cutaneous forms of adult mastocytosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We wanted to know if such a mast cell precursor exists among children with mastocytosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed 10 children with mastocytosis for c\u2010Kit+<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>34\u2010 mast cell precursors by flow cytometry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In contrast to adults with mastocytosis, we did not detect any circulating mast cell precursors by flow cytometry in the peripheral blood of children with mastocytosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical symptoms observed among children with cutaneous mastocytosis could be induced by cutaneous mast cell mediators and not by circulating mast cells. These results may help to better understand the differences between adult and childhood mastocytosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12182","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T09:35:37Z","timestamp":1371202537000},"page":"967-971","source":"Crossref","is-referenced-by-count":3,"title":["Absence of circulating mast cell precursors in paediatric mastocytosis: could it reflect a different pathophysiology between adults and children with mastocytosis?"],"prefix":"10.1111","volume":"28","author":[{"given":"S.","family":"Georgin\u2010Lavialle","sequence":"first","affiliation":[{"name":"CNRS UMR 8147 H\u00f4pital Necker\u2010Enfants malades Paris France"},{"name":"Centre de R\u00e9f\u00e9rence des Mastocytoses Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Le Sach\u00e9\u2010de Peufeilhoux","sequence":"additional","affiliation":[{"name":"Service de Dermatologie Universit\u00e9 Paris Descartes Paris Sorbonne Cit\u00e9 Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Martin","sequence":"additional","affiliation":[{"name":"Service de dermatologie Universit\u00e9 UNAM, h\u00f4pital d'Angers Angers France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Soucie","sequence":"additional","affiliation":[{"name":"Inserm U1068, CRCM,[ Signaling, Hematopoiesis and Mechanism of Oncogenesis]; Institut Paoli\u2010Calmettes, Marseille; Aix\u2010Marseille Univ; CNRS, UMR7258,CRCM Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Bruneau","sequence":"additional","affiliation":[{"name":"Laboratoire d'anatomopathologie Universit\u00e9 Paris Descartes, Paris Sorbonne Cit\u00e9, Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Institut Image Necker Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Barete","sequence":"additional","affiliation":[{"name":"CNRS UMR 8147 H\u00f4pital Necker\u2010Enfants malades Paris France"},{"name":"Centre de R\u00e9f\u00e9rence des Mastocytoses Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Dubreuil","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence des Mastocytoses Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Inserm U1068, CRCM,[ Signaling, Hematopoiesis and Mechanism of Oncogenesis]; Institut Paoli\u2010Calmettes, Marseille; Aix\u2010Marseille Univ; CNRS, UMR7258,CRCM Marseille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Bodemer","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence des Mastocytoses Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Service de Dermatologie Universit\u00e9 Paris Descartes Paris Sorbonne Cit\u00e9 Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Institut Image Necker Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Hermine","sequence":"additional","affiliation":[{"name":"CNRS UMR 8147 H\u00f4pital Necker\u2010Enfants malades Paris France"},{"name":"Centre de R\u00e9f\u00e9rence des Mastocytoses Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Service d'H\u00e9matologie Adultes Universit\u00e9 Paris Descartes, Paris Sorbonne Cit\u00e9, Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"},{"name":"Institut Image Necker Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Lhermitte","sequence":"additional","affiliation":[{"name":"CNRS UMR 8147 H\u00f4pital Necker\u2010Enfants malades Paris France"},{"name":"Laboratoire d'h\u00e9matologie Biologique et UMR CNRS 8147 Universit\u00e9 Paris Descartes, Paris Sorbonne Cit\u00e9, Facult\u00e9 de M\u00e9decine et AP\u2010HP Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,14]]},"reference":[{"volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","year":"2008","author":"Swerdlow SHCE","key":"e_1_2_6_2_1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23134"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(05)70299-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04365.x"},{"key":"e_1_2_6_6_1","first-page":"320","article-title":"Pediatric cutaneous mastocytosis: a review of 180 patients","volume":"7","author":"Ben\u2010Amitai D","year":"2005","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.281"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-335950"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(01)00050-9"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.10072"},{"key":"e_1_2_6_11_1","first-page":"1493","article-title":"Flow cytometric analysis of mast cells from normal and pathological human bone marrow samples: identification and enumeration","volume":"149","author":"Orfao A","year":"1996","journal-title":"Am J Pathol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01533368"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.7.2200"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/91.5.558"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1994.tb00560.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2012.02812.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12182","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:54:28Z","timestamp":1695556468000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,14]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/jdv.12182"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12182","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"type":"print","value":"0926-9959"},{"type":"electronic","value":"1468-3083"}],"subject":[],"published":{"date-parts":[[2013,6,14]]}}}