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The extracts of these ingredients, especially the hops, contain an abundance of polyphenols such as kaempferol, quercetin, tyrosol, ferulic acid, xanthohumol\/isoxanthohumol\/8\u2010prenylnaringenin, \u03b1\u2010bitter acids like humulone and \u03b2\u2010bitter acids like lupulone. 8\u2010prenylnaringenin is the most potent phytoestrogen known to date. These compounds have been shown to possess various anti\u2010bacterial, anti\u2010inflammatory, anti\u2010oxidative, anti\u2010angiogenic, anti\u2010melanogenic, anti\u2010osteoporotic and anti\u2010carcinogenic effects. Epidemiological studies on the association between beer drinking and skin disease are limited while direct evidence of beer compounds in clinical application is lacking. Potential uses of these substances in dermatology may include treatment of atopic eczema, contact dermatitis, pigmentary disorders, skin infections, skin ageing, skin cancers and photoprotections, which require an optimization of the biostability and topical delivery of these compounds. Further studies are needed to determine the bioavailability of these compounds and their possible beneficial health effects when taken by moderate beer consumption.<\/jats:p>","DOI":"10.1111\/jdv.12204","type":"journal-article","created":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T09:32:50Z","timestamp":1372325570000},"page":"142-150","source":"Crossref","is-referenced-by-count":48,"title":["Beer and beer compounds: physiological effects on skin health"],"prefix":"10.1111","volume":"28","author":[{"given":"W.","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Biederstein Technische Universit\u00e4t M\u00fcnchen Christine K\u00fchne Center for Allergy Research and Education (CK CARE) Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Becker","sequence":"additional","affiliation":[{"name":"Brewing and Beverage Technology Department of Life Science Engineering Center of Life and Food Sciences 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