{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T17:00:46Z","timestamp":1715965246170},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T00:00:00Z","timestamp":1372809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psoriasis vulgaris is a T\u2010cell mediated disease that affects 2\u20133% of the worldwide white\u2010skinned population. Fumaric acid esters are mentioned as an effective therapy for moderate\u2010to\u2010severe psoriasis vulgaris in adult patients in the new guidelines for psoriasis treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To obtain an insight into the use of fumaric acid esters by Dutch dermatologists in the Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional postal survey. An anonymous survey was posted to all Dutch dermatologists. In this survey, data were collected on the extent of fumaric acid esters use, the reasons for use, the reasons for non\u2010 or limited use of fumaric acid esters, the perception of fumaric acid esters as a mono\u2010therapy with regards to the effectiveness, the safety, the adverse events and the overall satisfaction of fumaric acid esters as a mono\u2010therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010three per cent of the 300 responders indicated to prescribe fumaric acid esters for the treatment of psoriasis. About 37% of the dermatologists indicated (almost) never to prescribe it. Biologicals were considered as the most effective therapy. Fumaric acid esters were regarded as the safest therapy. They were generally well\u2010tolerated by the patients similar to that for methotrexate according to the respondents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A large proportion of the dermatologists in our survey indicated to prescribe fumaric acid esters. It is considered to be effective, safe and without adverse events profile that is favourable in the practice, also as compared with other systemic therapies such as methotrexate and biologicals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12205","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T18:24:07Z","timestamp":1372875847000},"page":"972-975","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of psoriasis with non\u2010registered fumaric acid esters in The Netherlands: a nationwide survey among Dutch dermatologists"],"prefix":"10.1111","volume":"28","author":[{"given":"S.","family":"Fallah Arani","sequence":"first","affiliation":[{"name":"Department of Dermatology Albert Schweitzer Hospital Zwyndrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.M.W.","family":"Balak","sequence":"additional","affiliation":[{"name":"Department of Dermatology Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.A.M.","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Dermatology Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.V.","family":"Kuipers","sequence":"additional","affiliation":[{"name":"TEVA Nederland B.V. Haarlem The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.B.","family":"Thio","sequence":"additional","affiliation":[{"name":"Department of Dermatology Erasmus MC University Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.311"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.313"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.310"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0007-0963.2004.05739.x"},{"key":"e_1_2_6_6_1","first-page":"103","article-title":"Heilung von psoriasis vulgaris (Healing of psoriasis vulgaris)","volume":"13","author":"Schweckendiek W","year":"1959","journal-title":"Med Monatschr"},{"key":"e_1_2_6_7_1","first-page":"1260","article-title":"Fumarsaeure lindert die Schuppenflechte (Fumaric acid esters reduces scale formation)","volume":"15","author":"Schaefer GN","year":"1984","journal-title":"Selecta"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000247856"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10195.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03389.x"},{"key":"e_1_2_6_11_1","first-page":"1","article-title":"S3\u2010guidelines for the treatment of psoriasis vulgaris Update 2011","volume":"9","author":"Nast A","year":"2011","journal-title":"J Dtsch Dermatol Ges"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12205","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:54:32Z","timestamp":1695556472000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,3]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/jdv.12205"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12205","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,3]]}}}