{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T16:39:30Z","timestamp":1777653570578,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,3,5]],"date-time":"2014-03-05T00:00:00Z","timestamp":1393977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Evaluation of the local tumour control rate and survival data for magnetic resonance (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>) imaging\u2013guided laser ablation of uveal malignant melanoma liver metastases by using laser\u2010induced interstitial thermotherapy (<jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content> was performed in 18 patients with liver metastases (<jats:italic>n<\/jats:italic>\u00a0=\u00a044) from uveal malignant melanoma. All patients tolerated this intervention well. With the Kaplan\u2013Meier method, the survival rates were calculated. Indications for the procedure were defined for patients with no more than five metastases, none of which were larger than 5\u00a0cm in diameter: The Indication for <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content> treatment were recurrent liver metastases after partial liver resection (22%), locally non\u2010resectable tumours (17%) or metastases in both liver lobes (61%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean survival rate for all treated patients was 3.6\u00a0years (95% CI: 2.19, 5.06). We started the calculation on the date of diagnosis of the metastases treated with <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content>. The median survival was 1.83\u00a0years; 1\u2010year survival, 88%; 3\u2010year survival 47%, 5\u2010year survival 17%. Calculated after the first <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content> treatment the median survival was 2.8\u00a0years (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.0, 5.0). 10 patients were treated by transarterial chemoembolization before <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\u2010guided <jats:styled-content style=\"fixed-case\">LITT<\/jats:styled-content> treatment shows a high local tumour control and survival rates in patients with liver metastases of uveal malignant melanoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12405","type":"journal-article","created":{"date-parts":[[2014,3,5]],"date-time":"2014-03-05T10:08:40Z","timestamp":1394014120000},"page":"1756-1760","source":"Crossref","is-referenced-by-count":15,"title":["<scp>MR<\/scp>\u2010guided laser\u2010induced thermotherapy (<scp>LITT<\/scp>) in patients with liver metastases of uveal melanoma"],"prefix":"10.1111","volume":"28","author":[{"given":"K.","family":"Eichler","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Frankfurt Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Zangos","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Frankfurt Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Gruber\u2010Rouh","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Frankfurt Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.J.","family":"Vogl","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Frankfurt Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.G.","family":"Mack","sequence":"additional","affiliation":[{"name":"Radiology M\u00fcnchen Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a072986"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00078-2"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600521"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200208000-00016"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19951101)76:9<1665::AID-CNCR2820760925>3.0.CO;2-J"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2004.07.004"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(91)32285-1"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-1328"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.7748"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-006-0155-z"},{"key":"e_1_2_5_12_1","first-page":"131","article-title":"Intra\u2010arterial hepatic chemoembolization (TACE) of liver metastases from ocular melanoma with slow\u2010release irinotecan\u2010eluting beads. Early results of a phase II clinical study","volume":"23","author":"Fiorentini G","year":"2009","journal-title":"In Vivo."},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.03.064"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050732"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20001001)89:7<1561::AID-CNCR21>3.0.CO;2-R"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.136.8.950"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089169408000107"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2010.03.014"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3304-z"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9781-1"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.4881"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.170.3.2536946"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008390-200508000-00011"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820144"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2002.02205.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9101(2000)26:5<467::AID-LSM6>3.0.CO;2-8"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(01)00519-1"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12405","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12405","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:45:35Z","timestamp":1695570335000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,5]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/jdv.12405"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12405","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,5]]}}}