{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:02:01Z","timestamp":1792677721764,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T00:00:00Z","timestamp":1394755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Seoul National University Hospital Research Fund","award":["03-2007-0290"],"award-info":[{"award-number":["03-2007-0290"]}]},{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"crossref","award":["NFR-2010-0009075"],"award-info":[{"award-number":["NFR-2010-0009075"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Polycystic ovary syndrome (<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) is a common endocrinological disorder in women of childbearing\u2010age. Although <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> patients in Asia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The goal of this study is to elucidate the dermatological characteristics and metabolic and hormonal parameters of Korean <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> patients classified by the three <jats:styled-content style=\"fixed-case\">ASRM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">ESHERE<\/jats:styled-content> criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated 40 untreated <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> patients who were newly diagnosed in the Department of Obstetrics &amp; Gynecology of Seoul National University Hospital. Patients were classified according to the presence of irregular menstruation (<jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>), polycystic ovary morphology (<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content>) and hyperandrogenism (<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>). Acne specific questionnaire, physical examination, and blood sampling were thoroughly conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty four patients (60.0%) met the criteria for the <jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content> group and sixteen (40.0%) belonged to the <jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content> group. Acne was the most commonly observed dermatological manifestation (95.0%) followed by hirsutism (60.0%), seoborrhea (47.5%), acanthosis nigricans (20.0%) and androgenetic alopecia (12.5%). Hirsutism was more frequently observed in the <jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content> group; the prevalence of other cutaneous manifestations did not differ significantly. Acne was most often observed on the face and most acne lesions were distributed on the forehead and cheek. Serum dehydroepiandrosterone sulphate level was higher in <jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content> group, while serum cholesterol and high density lipoprotein concentrations were higher in the <jats:styled-content style=\"fixed-case\">IM<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PCOM<\/jats:styled-content> group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We described several dermatological manifestations and serum hormonal and metabolic parameters in Korean <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> patients. Cutaneous manifestations might be the first signs of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>; therefore, dermatologists should be more aware of cutaneous manifestations of various ethnicities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12432","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T08:13:00Z","timestamp":1394784780000},"page":"42-47","source":"Crossref","is-referenced-by-count":20,"title":["Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients"],"prefix":"10.1111","volume":"29","author":[{"given":"J.S.","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Dermatology Seoul National University College of Medicine Seoul Korea"},{"name":"Acne and Rosacea Research Laboratory Seoul National University Hospital Seoul 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