{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T08:50:16Z","timestamp":1713171016319},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,8,4]],"date-time":"2014-08-04T00:00:00Z","timestamp":1407110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Few published data, concerning the electron microscopy findings of idiopathic guttate hypomelanosis have been published so far.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To reveal the electron microscopic findings of idiopathic guttate hypomelanosis and their aetiopathogenetic associations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Punch biopsy specimens from four patients with idiopathic guttate hypomelanosis, after being properly processed, were observed under the electron microscope.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the epidermis, melanocytes and melanosomes were normal in structure. In some areas, there was a reduced uptake of melanosomes by the keratinocytes. In the dermis, fibroblasts were structurally normal. Also, most elastic and collagen fibres were normal, but there were focal elastotic changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>No significant structural abnormality of the melanocytes was observed, but rather a functional defect in the transfer of melanosomes from the melanocytes to the keratinocytes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12646","type":"journal-article","created":{"date-parts":[[2014,8,4]],"date-time":"2014-08-04T04:22:01Z","timestamp":1407126121000},"page":"1435-1438","source":"Crossref","is-referenced-by-count":13,"title":["Idiopathic guttate hypomelanosis: an electron microscopy study"],"prefix":"10.1111","volume":"29","author":[{"given":"M.","family":"Kakepis","sequence":"first","affiliation":[{"name":"Department of Dermatology \u2018Henry Dunant\u2019 Hospital Athens Greece"},{"name":"2nd Department of Dermatology and Venereology National and Kapodistrian University of Athens Medical School \u2018Attikon\u2019 General University Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Havaki","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology National and Kapodistrian University of Athens Medical School Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Katoulis","sequence":"additional","affiliation":[{"name":"2nd Department of Dermatology and Venereology National and Kapodistrian University of Athens Medical School \u2018Attikon\u2019 General University Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Katsambas","sequence":"additional","affiliation":[{"name":"1st Department of Dermatology and Venereology National and Kapodistrian University of Athens Medical School \u2018Andreas Syggros\u2019 Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Stavrianeas","sequence":"additional","affiliation":[{"name":"2nd Department of Dermatology and Venereology National and Kapodistrian University of Athens Medical School \u2018Attikon\u2019 General University Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.G.","family":"Troupis","sequence":"additional","affiliation":[{"name":"Department of Anatomy National and Kapodistrian University of Athens Medical School Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1966.01600200040005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(87)70003-6"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04743.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1001\/archderm.1966.01600270029005","article-title":"Idiopathic guttate hypomelanosis","volume":"94","author":"William C","year":"1966","journal-title":"Arch 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