{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T21:00:00Z","timestamp":1781125200774,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Veterans Affairs Council of the Executive Yuan of Taiwan","award":["VAC100-C11"],"award-info":[{"award-number":["VAC100-C11"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Backgrounds<\/jats:title><jats:p>Diabetes mellitus (<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>) is a common endocrine disorder and an increasing epidemic worldwide. Proportional diabetic patients eventually develop cutaneous diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study determined the statistical association of cutaneous manifestations and <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> as well as the <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\u2010associated cutaneous manifestations in elderly male residents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted in a Veterans Home in Taiwan. The cutaneous manifestations and major systemic diseases of the residents were recorded separately. Univariate logistic regression and multivariate analysis after adjustment for age, body mass index and significant major systemic diseases provided odds ratios and <jats:italic>P<\/jats:italic> values for the statistical association.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 313 male residents (age \u226565\u00a0years) were recruited, including 70 (22.4%) with <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>. Their most common cutaneous manifestations included fungal infection (77%) and brown spots on the legs (38.3%). Chronic ulcers adjusted odds ratios (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 4.90, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.82\u201313.19; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002), brown spots on the legs (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 6.82, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 3.60\u201312.89; <jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.001) and pruritus (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 12.86, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 4.40\u201337.59; <jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.001) were significantly associated with <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>. The diabetic residents were inclined to have chronic ulcers, brown spots on the legs and pruritus at a 7.46\u2010fold higher risk (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 7.46, 95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 3.86\u201314.43; <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). The diabetic residents exhibited marginally higher risks of bacterial infection, scabies, or skin tags.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\u2010associated cutaneous manifestations were chronic ulcers, brown spots on the legs, and pruritus. By observing clues of diabetic cutaneous features, a more complete condition of diabetic patients can be appreciated. The information is essential for providing appropriate treatment and key nursing points regarding the diabetes\u2010associated skin diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12664","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T11:55:36Z","timestamp":1409572536000},"page":"1631-1635","source":"Crossref","is-referenced-by-count":34,"title":["High prevalence of cutaneous manifestations in the elderly with diabetes mellitus: an institution\u2010based cross\u2010sectional study in Taiwan"],"prefix":"10.1111","volume":"29","author":[{"given":"H.\u2010W.","family":"Tseng","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Department of Nursing Meiho University Neipu Pingtung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.\u2010P.","family":"Ger","sequence":"additional","affiliation":[{"name":"Department of Medical Education and Research Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Institute of Biomedical Sciences National Sun Yat\u2010Sen University Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.\u2010K.","family":"Liang","sequence":"additional","affiliation":[{"name":"Center for Geriatrics and Gerontology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Aging and Health Research Center National Yang Ming University Taipei Taiwan"},{"name":"Division of Neurology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010H.","family":"Liou","sequence":"additional","affiliation":[{"name":"Department of Medical Education and Research Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010C.","family":"Lam","sequence":"additional","affiliation":[{"name":"Center for Geriatrics and Gerontology Kaohsiung Veterans General Hospital Kaohsiung Taiwan"},{"name":"Division of Endocrinology and Metabolism Department of Internal Medicine Kaohsiung Veterans General Hospital Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2012.09.014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-4543(05)70201-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.4.506"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2006.01918.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02553.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1984.tb05694.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70058-3"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2007.10.015"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-0407.2011.00151.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04475.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2012.09.006"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1001\/archderm.1966.01600210018003","article-title":"Pigmented pretibial patches. 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