{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:09:34Z","timestamp":1784822974611,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T00:00:00Z","timestamp":1414454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Non\u2010cultured cellular grafting is specified for stable vitiligo treatment as a novel surgical technique, however, the additive effect of excimer laser on melanocytes\u2013keratinocytes transplantation (MKT) have not experienced yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assay the additive effect of excimer laser on MKT for the treatment of vitiligo in an Iranian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>In this non\u2010randomized clinical trial, 39 patches were evaluated. Nine patches treated by MKT alone, 10 patches treated by MKT and excimer laser, 10 patches treated with excimer alone and 10 patches left without any treatments as control patches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the patches treated with excimer, the percentage reduction of depigmented area from baseline varied, ranging from 0 to 43.9%. In the nine patches treated with non\u2010cultured MKT, the median percentage reduction of depigmented area from baseline was 15.9%. The median percentage reduction of depigmented area in excimer\u00a0+\u00a0MKT was 41.9% .In the untreated patches, the median percentage reduction of depigmented area was 0.1%. After controlling for the effect of \u2018depigmented area at baseline\u2019, significant reductions were observed in depigmented area of the patches treated with combination therapy of excimer and non\u2010cultured MKT in comparison with the other therapies and untreated patches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although pigmentation in our patients was lower than previous reports from Iran and other countries, however, we signified adding excimer to MKT increased the pigmentation rate in treated patches. Further investigations are recommended with longer follow\u2010up and larger series to validate the findings reported here.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12674","type":"journal-article","created":{"date-parts":[[2014,10,29]],"date-time":"2014-10-29T02:12:02Z","timestamp":1414548722000},"page":"745-751","source":"Crossref","is-referenced-by-count":30,"title":["The additive effect of excimer laser on non\u2010cultured melanocyte\u2013keratinocyte transplantation for the treatment of vitiligo: a clinical trial in an Iranian population"],"prefix":"10.1111","volume":"29","author":[{"given":"A.","family":"Ebadi","sequence":"first","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences Shohada\u2010e\u2010tajrish Hospital Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.M.","family":"Rad","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences Shohada\u2010e\u2010tajrish Hospital Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Nazari","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences Shohada\u2010e\u2010tajrish Hospital Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.J.","family":"Fesharaki","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences Shohada\u2010e\u2010tajrish Hospital Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ghalamkarpour","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences Shohada\u2010e\u2010tajrish Hospital Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Younespour","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics School of Public Health Tehran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01628.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2003.20304.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12006"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2004.00825.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470987568.ch8"},{"key":"e_1_2_6_7_1","first-page":"215","article-title":"Autologous melanocyte\u2013keratinocyte suspension in the treatment of vitiligo","volume":"25","author":"El\u2010Zawahry BM","year":"2011","journal-title":"JEADV"},{"key":"e_1_2_6_8_1","first-page":"1182","article-title":"Non\u2010cultured melanocyte\u2010keratinocyte transplantation for the treatment of vitiligo: a clinical trial in an Iranian population","volume":"25","author":"Toossi P","year":"2011","journal-title":"JEADV"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70024-A"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02177.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/00042728-200502000-00006","article-title":"Autologous epidermal cultures and narrow\u2010band ultraviolet B in the surgical treatment of vitiligo","volume":"31","author":"Pianigiani E","year":"2005","journal-title":"Dermatol Surg"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10014.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02226.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.10.1211"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.415"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.53101"},{"key":"e_1_2_6_17_1","first-page":"37","article-title":"Standard guidelines of care for vitiligo surgery","volume":"74","author":"Parsad D","year":"2008","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04837.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000092833"},{"key":"e_1_2_6_20_1","first-page":"66","article-title":"Treatment of vitiligo on difficultto\u2010treat sites using autologous noncultured cellular grafting","volume":"35","author":"Mulekar SV","year":"2009","journal-title":"Dermatol Surg"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.45106"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01045.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12674","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:23:59Z","timestamp":1695471839000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,28]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/jdv.12674"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12674","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,28]]}}}