{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:12:42Z","timestamp":1792271562693,"version":"4.4.0"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T00:00:00Z","timestamp":1410134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Up to present no curative treatment is known for Dupuytren's disease (DD). Surgery remains the most common treatment but lack of long\u2010term efficacy and complications limit this therapeutic option.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>In a retrospective analysis, the results of radiotherapy with soft X\u2010rays in the treatment of DD were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 206 patients (297 affected hands) with DD were included. Radiation therapy was carried out with soft X\u2010rays. A structured questionnaire considering patient and disease characteristics and effects of radiotherapy was evaluated after a median follow\u2010up time of 40\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010three (45%) of the 206 treated patients were reported on a regression of symptoms after radiation. No further disease progression (including patients with regression) was present in 165 patients (80%). Satisfaction with the therapy was expressed with an average score of 7.9 points (visual analogue scale, 0\u00a0=\u00a0not satisfied, 10\u00a0=\u00a0extremely satisfied). Subjective therapeutic effects for 426 nodules and\/or cords showed a reduction of 92 nodules and\/or cords.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In 206 DD patients further disease progression was stopped in most patients. Radiotherapy proved to be well\u2010tolerated, successful and satisfying for the patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12711","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T15:39:36Z","timestamp":1410190776000},"page":"904-911","source":"Crossref","is-referenced-by-count":20,"title":["Radiotherapy with soft X\u2010rays in Dupuytren's disease \u2013 successful, well\u2010tolerated and satisfying"],"prefix":"10.1111","volume":"29","author":[{"given":"M.","family":"Zirbs","sequence":"first","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Dermatologie und Allergologie am Biederstein, Klinikum rechts der Isar Technische Universit\u00e4t M\u00fcnchen Munich Germany"},{"name":"Christine K\u00fchne Center for Allergy Research and Education (CK\u2010CARE) M\u00fcnchen, Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Anzeneder","sequence":"additional","affiliation":[{"name":"Klinik und 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