{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T10:31:20Z","timestamp":1777285880446,"version":"3.51.4"},"reference-count":53,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T00:00:00Z","timestamp":1412640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ingredients of leave\u2010on cosmetics and body care products may sensitize. However, not every case of cosmetic intolerance is due to contact sensitization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the frequency of contact sensitization due to cosmetics in a large clinic population, and a possible particular allergen pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of data from the Information Network of Departments of Dermatology, 2006\u20132011.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 69\u00a0487 patients tested, \u2018cosmetics, creams, sunscreens\u2019 was the only suspected allergen source category in 10\u00a0124 patients (14.6%). A final diagnosis \u2018allergic contact dermatitis\u2019 was stated in 2658 of these patients (26.3%).Compared to a control group, there were significantly more reactions to fragrance mixes I and II, balsam of Peru, methylchloroisothiazolinone\/methylisothiazolinone (<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>) and lanolin alcohols. No special pattern of fragrance sensitization could be identified. Among the preservatives, <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> was by far the leading allergen, while sensitization to other widely used compounds like parabens or phenoxyethanol was rare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>True allergic reactions to cosmetic ingredients are rarer than generally assumed. Limitation of exposure to <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> in leave\u2010on cosmetics and body care products is urgently needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12750","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T09:40:38Z","timestamp":1412674838000},"page":"1071-1081","source":"Crossref","is-referenced-by-count":47,"title":["Contact sensitization in patients with suspected cosmetic intolerance: results of the <scp>IVDK<\/scp> 2006\u20132011"],"prefix":"10.1111","volume":"29","author":[{"given":"A.","family":"Dinkloh","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Allergy Charit\u00e9 Universit\u00e4tsmedizin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Worm","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergy Charit\u00e9 Universit\u00e4tsmedizin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Geier","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology Georg\u2010August University G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schnuch","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology Georg\u2010August University G\u00f6ttingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Wollenberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Allergy Ludwig\u2010Maximilians\u2010Universit\u00e4t Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.01051.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000063379"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200405050-00006"},{"key":"e_1_2_7_5_1","unstructured":"SchnuchA.Report on the national pilot studies on a harmonized and pragmatic cosmetovigilance system in the partial agreement member states. 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