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This prevents sebum drainage, causing the formation of microcomedones, which spontaneously regress or become acne lesions when the pilosebaceous unit is further blocked by the accumulation of corneocytes. These conditions are favourable for the proliferation of <jats:italic>Propionibacterium acnes<\/jats:italic>, which further aggravates acne by enhancing abnormal desquamation, sebum production and inflammation. Also, skin fragility due to inflammation or irritation by anti\u2010comedogenic agents can worsen the situation. Rhealba<jats:sup>\u00ae<\/jats:sup> Oat plantlet extract (Pierre Fabre Dermo Cosmetique) soothes and restores fragile skin in acne by reducing inflammation and inhibits bacterial adhesion of <jats:italic>Propionibacterium acnes<\/jats:italic>. Cosmeceuticals combining Rhealba<jats:sup>\u00ae<\/jats:sup> Oat plantlet extract and hydro\u2010compensating actives, which are available with or without anti\u2010comedogenic hydroxy acids, provide a balanced, multifaceted approach for acne patients.<\/jats:p>","DOI":"10.1111\/jdv.12791","type":"journal-article","created":{"date-parts":[[2014,11,26]],"date-time":"2014-11-26T16:09:09Z","timestamp":1417018149000},"page":"1-6","source":"Crossref","is-referenced-by-count":25,"title":["Cosmeceuticals based on Rhealba<sup>\u00ae<\/sup> Oat plantlet extract for the treatment of acne vulgaris"],"prefix":"10.1111","volume":"28","author":[{"given":"G.","family":"Fabbrocini","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Saint Aroman","sequence":"additional","affiliation":[{"name":"Pierre Fabre Dermo\u2010Cosm\u00e9tique 81500 Lavaur France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60321-8"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12149"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2011.07.002"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.23"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04214.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1998.00143.x"},{"key":"e_1_2_5_8_1","first-page":"27","article-title":"The role of inflammation in the pathology of acne","volume":"6","author":"Tanghetti EA","year":"2013","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-012-1265-x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12398620"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12049"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2013.740456"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10375.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-5945-13-10"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12252"},{"key":"e_1_2_5_16_1","first-page":"626","article-title":"Clinical relevance of skin barrier changes associated with the use of oral isotretinoin: the importance of barrier repair therapy in patient management","volume":"12","author":"Del Rosso JQ","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_17_1","article-title":"Fragility of epidermis and its consequence in dermatology","volume":"28","author":"Stadler JF","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"e_1_2_5_18_1","first-page":"18","article-title":"Acne vulgaris and the epidermal barrier: is acne vulgaris associated with inherent epidermal abnormalities that cause impairment of barrier functions? 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