{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:19:11Z","timestamp":1772223551669,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,12,3]],"date-time":"2014-12-03T00:00:00Z","timestamp":1417564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ketoprofen Consortium"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Photoallergic contact dermatitis (<jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content>) is an uncommon condition, and there is a lack of validated criteria for its diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify a set of relevant criteria to be considered when suspecting a diagnosis of <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content> and to assess the reproducibility of these criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a diagnostic item selection and reliability study performed between July 2012 and October 2012. A panel of seven recognized experts was invited to consecutive rounds of a Delphi survey and to a conclusive face\u2010to\u2010face meeting with the aim of obtaining an agreement on criteria for the diagnosis of <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content>. The panel was also provided with a series of 16 reports of suspected <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content>s to be classified according to a five\u2010point likelihood scale. Identified criteria with the weights attributed by experts were used to develop a score system for the diagnosis of <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content>. Consensus was measured by calculating the Intraclass Correlation Coefficient (<jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>). The performance of the score system was evaluated in terms of overall classification accuracy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven criteria were identified by experts as relevant for the diagnosis of <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content>. The criteria were related to the type of skin lesions, accompanying symptoms, skin area involved, general medical history, modality of exposure to the culprit substance, history of exposure to the sun or other light sources and photopatch test results. Experts reached a moderate agreement on <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content> cases classification, with <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\u00a0=\u00a00.69 (95% Confidence Interval, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 0.50\u20130.86). The score system enabled discrimination of probable and definite <jats:styled-content style=\"fixed-case\">PACD<\/jats:styled-content> cases from possible and unlikely or excluded ones, with a nearly perfect agreement being observed between the score system classification and judgment by experts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A diagnostic score was proposed. The score should receive a comprehensive validation on a larger series of cases and with multiple evaluators.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12879","type":"journal-article","created":{"date-parts":[[2014,12,4]],"date-time":"2014-12-04T02:04:04Z","timestamp":1417658644000},"page":"1376-1381","source":"Crossref","is-referenced-by-count":11,"title":["Development of a clinical score system for the diagnosis of photoallergic contact dermatitis using a consensus process: item selection and reliability"],"prefix":"10.1111","volume":"29","author":[{"given":"S.","family":"Cazzaniga","sequence":"first","affiliation":[{"name":"Centro Studi GISED \u2010 FROM Bergamo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Lecchi","sequence":"additional","affiliation":[{"name":"Centro Studi GISED \u2010 FROM Bergamo 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