{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:20:31Z","timestamp":1772223631614,"version":"3.50.1"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T00:00:00Z","timestamp":1422230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There has been an increase in methylchloroisothiazolinone (<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>) and especially methylisothiazolinone (<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>) contact allergy in recent years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We examined the prevalence and demography of <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> contact allergy in patients presenting with facial dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty patients with facial dermatitis were patch tested to the <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ritish <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ociety for <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>utaneous <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>llergy standard series, preservatives and own products between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2012 and <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 14 (17.5%) patients had positive reactions to this preservative. Five (6.3%) patients tested positive to <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> (0.02%), four (5%) patients tested positive to <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> (0.2%) and five (6.3%) patients tested positive to both preparations. Six (7.5%) of these patients were atopic. All patients were female and the mean age was 53.8\u00a0years. Sources of allergen were in cosmetics and skin care products.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Contact allergies to <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> are commoner than what was reported before and is an emerging cause of facial dermatitis. The detection rate of this allergen was increased by 5% in our cohort since the inclusion of <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> (0.2%) in the standard series.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.12956","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T12:11:53Z","timestamp":1422274313000},"page":"60-62","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence of methylchloroisothiazolinone and methylisothiazolinone contact allergy in facial dermatitis: a single centre <scp>I<\/scp>rish study"],"prefix":"10.1111","volume":"30","author":[{"given":"A.","family":"Murad","sequence":"first","affiliation":[{"name":"Department of Dermatology University College Hospital Galway Galway Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Marren","sequence":"additional","affiliation":[{"name":"Department of Dermatology University College Hospital Galway Galway Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12098"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10523.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12249"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12286"},{"issue":"9","key":"e_1_2_6_6_1","first-page":"854","article-title":"Descriptive study of sensitization to methylchloroisothiazolinone and methylisothiazolinone in a skin allergy unit","volume":"105","author":"Unamuno B","year":"2014","journal-title":"Actas Dermosifiliogr"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e3182811432"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12150"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2012.02157.x"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12956","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12956","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12956","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:20:57Z","timestamp":1695550857000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,26]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1111\/jdv.12956"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12956","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,26]]}}}