{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:32:01Z","timestamp":1777455121276,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T00:00:00Z","timestamp":1423008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tobacco smoking is known to influence various inflammatory skin diseases. A systematic review with a meta\u2010analysis was conducted to analyse a possible association between the lifestyle factor tobacco smoking and hand dermatitis. We performed a systematic review using the <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>, Embase and Cochrane Central Register databases. Our search was limited to English and German language, human\u2010subject studies published between January 1, 1980 and December 31, 2013. A total of 43 articles were identified from the initial search, and after taking into account exclusion criteria, only three studies remained investigating the risk factors for hand eczema in the general and in high\u2010risk populations (e.g. bakers, hairdressers, dental technicians). The extracted data were pooled and analysed by standard statistical methods. The studies meeting inclusion criteria consisted of one cohort study and two cross\u2010sectional studies based on a total of 4.113 subjects with hand dermatitis and 34.875 subjects without hand dermatitis. While one of the studies had reported a significant association between hand dermatitis and smoking, the meta\u2010analysis did not confirm this finding (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.99; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.88\u20131.11). However, heterogeneity across studies was high (<jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a072%). Our meta\u2010analysis did not show tobacco smoking to be a risk factor for hand dermatitis. However, these results depend mainly on two large studies from one country. From present data, it cannot be excluded that smoking may influence the course of hand dermatitis. Even though smoking does not seem to be associated with hand dermatitis, it may still negatively influence the course of the disease.<\/jats:p>","DOI":"10.1111\/jdv.12971","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T10:35:51Z","timestamp":1423046151000},"page":"1280-1284","source":"Crossref","is-referenced-by-count":30,"title":["Association between smoking and hand dermatitis \u2013 a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"29","author":[{"given":"J.","family":"Luk\u00e1cs","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Schliemann","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Elsner","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.01718.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01179.x"},{"key":"e_1_2_5_4_1","first-page":"4","article-title":"Smoking and skin disease","volume":"15","author":"Thomsen SF","year":"2010","journal-title":"Skin Therapy Lett"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.005"},{"key":"e_1_2_5_6_1","volume-title":"Review Manager (RevMan) [Computer program]. 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