{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:35:39Z","timestamp":1790141739761,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T00:00:00Z","timestamp":1422403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Galderma International, Paris, France"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Daylight\u2010mediated photodynamic therapy has been shown to be an effective therapy for actinic keratoses (\n                      <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\n                      s) and a simple and tolerable treatment procedure in three randomized Scandinavian studies and two recent Phase\n                      <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\n                      randomized controlled studies in Australia and Europe.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To establish consensus recommendations for the use of daylight photodynamic therapy (\n                      <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      ) using topical methyl aminolaevulinate (\n                      <jats:styled-content style=\"fixed-case\">MAL<\/jats:styled-content>\n                      ) in European patients with AKs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      consensus recommendations were developed on behalf of the European Society for Photodynamic Therapy in Dermatology and comprised of 10 dermatologists from different European countries with experience in how to treat\n                      <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\n                      patients with\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      . Consensus was developed based on literature review and experience of the experts in the treatment of\n                      <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\n                      using\n                      <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The recommendations arising from this panel of experts provide general guidance on the use of\n                      <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      as a dermatological procedure with specific guidance regarding patient selection, therapeutic indications, when to treat, pre\u2010treatment skin preparation,\n                      <jats:styled-content style=\"fixed-case\">MAL<\/jats:styled-content>\n                      application and daylight exposure for patients with\n                      <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\n                      in different countries of Europe.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This consensus recommendation provides a framework for physicians to perform\n                      <jats:styled-content style=\"fixed-case\">DL<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content>\n                      with\n                      <jats:styled-content style=\"fixed-case\">MAL<\/jats:styled-content>\n                      cream while ensuring efficiency and safety in the treatment of patients with\n                      <jats:styled-content style=\"fixed-case\">AK<\/jats:styled-content>\n                      in different European countries.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.12974","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T05:39:22Z","timestamp":1422423562000},"page":"1718-1723","source":"Crossref","is-referenced-by-count":95,"title":["Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus"],"prefix":"10.1111","volume":"29","author":[{"given":"C.A.","family":"Morton","sequence":"first","affiliation":[{"name":"Department of Dermatology Stirling Community Hospital Stirling UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.C.","family":"Wulf","sequence":"additional","affiliation":[{"name":"Department of Dermatology Bispebjerg Hospital University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.M.","family":"Szeimies","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Klinikum Vest GmbH Academic Teaching Hospital Recklinghausen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Gilaberte","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital San Jorge Huesca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Basset\u2010Seguin","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Dermatologie H\u00f4pital Saint\u2010Louis Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Sotiriou","sequence":"additional","affiliation":[{"name":"First Dermatology Department Aristotle University Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Piaserico","sequence":"additional","affiliation":[{"name":"Unit of Dermatology Department of Medicine University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.E.","family":"Hunger","sequence":"additional","affiliation":[{"name":"Department of Dermatology Inselspital University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Baharlou","sequence":"additional","affiliation":[{"name":"Department of Dermatology Vrije Universiteit Brussel (VUB) Universitair Ziekenhuis UZ Brussel Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sidoroff","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Medical University, Innsbruck Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. R.","family":"Braathen","sequence":"additional","affiliation":[{"name":"Dermatology Bern Im Holenacker 16 CH\u20103063 Ittigen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08450.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09119.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10209.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13138"},{"key":"e_1_2_7_6_1","unstructured":"LacourJ.Results of 2 randomised controlled phase III studies with Daylight\u2010PDT in Australia and Europe. Euro\u2010PDT 14th Annual Congress; April 4th\u20135th 2014;Nice France."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04386.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12076"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13222"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.10833.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1425"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550510042868"},{"key":"e_1_2_7_13_1","first-page":"307","article-title":"Photodynamic therapy vs. imiquimod 5% cream as skin cancer preventive strategies in patients with field changes: a randomized intraindividual comparison study","volume":"29","author":"Sotiriou E","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"e_1_2_7_14_1","unstructured":"Personal communication Galderma data on file."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11200.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12882"},{"key":"e_1_2_7_17_1","unstructured":"Osman\u2010PonchetH.Effect of sunscreen on Metvix absorption in ex\u2010vivo human skin. Euro\u2010PDT 14th Annual Congress; April 4th\u20135th 2014;Nice France."},{"key":"e_1_2_7_18_1","unstructured":"SevinK.Effect of sunscreen on protoporphyrin IX photobleaching in ex vivo human skin. Euro\u2010PDT 14th Annual Congress; April 4th\u20135th 2014;Nice France."},{"key":"e_1_2_7_19_1","unstructured":"GholamP.Influence of pre\u2010treatment with urea cream 40% on face and scalp AK on efficacy and tolerability. Euro\u2010PDT 14th Annual Congress; April 4th\u20135th 2014;Nice France."},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12119_suppl"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12127"},{"key":"e_1_2_7_22_1","unstructured":"WulfHC.Optimizing the amount of Metvix in daylight PDT. Euro\u2010PDT 13th Annual Congress; May 31st\u2013June 1st 2013;Madrid Spain."},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12142"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13284"},{"key":"e_1_2_7_25_1","article-title":"Daylight photodynamic therapy with methyl aminolaevulinate in patients with actinic keratoses: a preliminary experience in southern Italy","author":"Fai D","year":"2014","journal-title":"G Ital Dermatol Venereol"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2013.10.021"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12974","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.12974","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.12974","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T14:12:15Z","timestamp":1695478335000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.12974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,28]]},"references-count":25,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1111\/jdv.12974"],"URL":"https:\/\/doi.org\/10.1111\/jdv.12974","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,28]]}}}