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Three groups were assessed: stage I\/II<\/jats:styled-content>, resected stage III<\/jats:styled-content> and unresectable stage III<\/jats:styled-content>\/stage IV<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>The median follow\u2010up time of living patients was 43.48\u00a0\u00b1\u00a019.67 (15\u2013142) months. We observed a high diagnostic accuracy in all stages (91.3%, 92.5% and 96.2% respectively). PET<\/jats:styled-content>\/CT<\/jats:styled-content> appeared to be reliable diagnostic tool even for the detection of small lymph node metastases. PET<\/jats:styled-content>\/CT<\/jats:styled-content> was informative in 14 of 19 cases wherein another imaging examination provided inconclusive results regarding lesion dignity. However, PET<\/jats:styled-content>\/CT<\/jats:styled-content> was less suitable for properly evaluating the dignity of a lung lesion. A true positive scan was twice as likely in clinically negative patients with resected stage III<\/jats:styled-content> disease than in patients with stage I\/II<\/jats:styled-content> disease (35.9% and 14.5%, P\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.007).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>These results confirm that PET<\/jats:styled-content>\/CT<\/jats:styled-content> is an important diagnostic tool in the management of patients with high\u2010risk CMM<\/jats:styled-content>, but it cannot replace the standard of care examinations. More accurate clinicopathological and timing criteria must be defined to best utilize the advantages of this imaging method.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13084","type":"journal-article","created":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T07:50:38Z","timestamp":1425887438000},"page":"1938-1944","source":"Crossref","is-referenced-by-count":21,"title":["Diagnostic accuracy of 18<\/sup>F\u2010FDG<\/scp>\u2010PET<\/scp>\/CT<\/scp> in early and late stages of high\u2010risk cutaneous malignant melanoma"],"prefix":"10.1111","volume":"29","author":[{"given":"E.","family":"Gell\u00e9n","sequence":"first","affiliation":[{"name":"Department of Dermatology Faculty of Medicine University of Debrecen Debrecen Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"S\u00e1ntha","sequence":"additional","affiliation":[{"name":"Scanomed Ltd. 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