{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T07:35:53Z","timestamp":1780817753071,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,3,23]],"date-time":"2015-03-23T00:00:00Z","timestamp":1427068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Regional cancer center South East in Link\u00f6ping"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,5]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Clinical stage at diagnosis is a strong prognostic factor for death in cutaneous malignant melanoma (CMM<\/jats:styled-content>), with worse prognosis at higher stages. However, few studies have investigated how direct health care cost per patient varies with clinical stage.<\/jats:p><\/jats:sec>Objective<\/jats:title>The aim of this study was to determine the stage\u2010specific direct health care costs for CMM<\/jats:styled-content> patients compared to the health care costs in the general population in the County of \u00d6sterg\u00f6tland, Sweden.<\/jats:p><\/jats:sec>Methods<\/jats:title>Cutaneous malignant melanoma patients in the County of \u00d6sterg\u00f6tland diagnosed 2005\u20132012 were identified from the Swedish cancer registry. Information on clinical stage was collected from the Swedish Melanoma Register (SMR<\/jats:styled-content>) and cost data from the Cost per Patient database (CPP<\/jats:styled-content>) for 1075 CMM<\/jats:styled-content> patients in \u00d6sterg\u00f6tland. CPP<\/jats:styled-content> contains costs associated with all health care contacts per patient including inpatient, outpatient and primary care. The CMM<\/jats:styled-content>\u2010related costs were defined as the difference in mean health care costs between CMM<\/jats:styled-content> patients and general population.<\/jats:p><\/jats:sec>Results<\/jats:title>The first year after CMM<\/jats:styled-content> diagnosis, the average health care costs for CMM<\/jats:styled-content> patients were 2.8 times higher than in the general population. The health care cost ratio varied from 2.0 (stage I) to 10.1 (stage IV<\/jats:styled-content>) and the CMM<\/jats:styled-content>\u2010related costs per patient\u2010year varied from \u20ac2 670 (stage I) to \u20ac29 291 (stage IV<\/jats:styled-content>). The mean health care costs decreased over time but remained significantly higher than in the general population for all clinical stages. During the first year after diagnosis, patients in clinical stage III<\/jats:styled-content>\u2013IV<\/jats:styled-content> (7% of CMM<\/jats:styled-content> patients) accounted for 27% of the total CMM<\/jats:styled-content>\u2010related health care costs.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The direct health care costs for CMM<\/jats:styled-content> patients were significantly higher than in the general population independent of clinical stage. CMM<\/jats:styled-content> patients diagnosed in clinical stage III<\/jats:styled-content>\u2013IV<\/jats:styled-content> were associated with particularly high costs and the health care system may save resources by finding CMM<\/jats:styled-content> patients in earlier stages.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13110","type":"journal-article","created":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T19:43:32Z","timestamp":1427226212000},"page":"789-793","source":"Crossref","is-referenced-by-count":19,"title":["Stage\u2010specific direct health care costs in patients with cutaneous malignant melanoma"],"prefix":"10.1111","volume":"30","author":[{"given":"J.","family":"Lyth","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Regional Cancer Center South East University Hospital Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Carstensen","sequence":"additional","affiliation":[{"name":"Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Synnerstad","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lindholm","sequence":"additional","affiliation":[{"name":"Regional Cancer Center South East University Hospital Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,23]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Cancer Incidence in Sweden 2013.National Board of Health and Welfare Stockholm Sweden.2014. Available at:http:\/\/www.socialstyrelsen.se\/Lists\/Artikelkatalog\/Attachments\/19613\/2014-12-10.pdf(last accessed: 18 December 2014)."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13483"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27616"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.389"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5070\/D353F8Q915","article-title":"Melanoma costs: a dynamic model comparing estimated overall costs of various clinical stages","volume":"15","author":"Alexandrescu DT","year":"2009","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70195-1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-009-9350-y"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2008.02444.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12095"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2013.03.013"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.52.7564"},{"key":"e_1_2_6_13_1","volume-title":"Essential Medical Statistics","author":"Kirkwood BR","year":"2003"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e328360150c"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0b013e3282f36203"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70072-5"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13110","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13110","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.13110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:58:52Z","timestamp":1695513532000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.13110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,23]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/jdv.13110"],"URL":"https:\/\/doi.org\/10.1111\/jdv.13110","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,23]]}}}