{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:29:04Z","timestamp":1790504944741,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,4,13]],"date-time":"2015-04-13T00:00:00Z","timestamp":1428883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Vitiligo is a common depigmenting skin disorder that can influence a patient's quality of life. Although patient\u2010orientated medicine is an emerging concept, a self\u2010assessment tool to assess the degree of depigmentation in vitiligo is not yet available. Therefore, we developed the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      , a self\u2010assessment tool that uses the same basic principles as the\n                      <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To assess the validity, reliability and acceptability of the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      To assess the validity of the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      , we compared the scores assessed by the patient with the scores of the\n                      <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>\n                      assessed by the physician. To assess the intra\u2010rater reliability, the correlation between the baseline\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      and the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      after 2\u00a0weeks was calculated. To assess the acceptability, patients indicated the time needed to complete the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      and the patient assessed the difficulty of the questionnaire on a five\u2010point scale. The Skindex\u201029 was used to determine the quality of life. The overestimation of the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      compared to the\n                      <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>\n                      was calculated by subtracting the\n                      <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>\n                      scores off from the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A high correlation between the\n                      <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>\n                      and the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\n                      0.97, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 0.95\u20130.98) was found in 60 patients. The intra\u2010rater reliability of the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\n                      0.75, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.54\u20130.87) was adequate in 31 patients. Fifty (83%) of the patients completed the questionnaire within 10\u00a0min and only five (8%) of the patients considered the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      hard. We found no correlation between overestimation of the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      score and the Skindex\u201029 score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      is a valid, reliable and acceptable self\u2010assessment tool to measure the degree of depigmentation in vitiligo. With the\n                      <jats:styled-content style=\"fixed-case\">SAVASI<\/jats:styled-content>\n                      the degree of depigmentation can reliably be assessed by the patient themselves which can be useful in large (epidemiological) studies. Furthermore, this could contribute to the patient's disease insight and therapy loyalty.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jdv.13161","type":"journal-article","created":{"date-parts":[[2015,4,13]],"date-time":"2015-04-13T06:39:37Z","timestamp":1428907177000},"page":"2145-2151","source":"Crossref","is-referenced-by-count":18,"title":["The validity, reliability and acceptability of the\n                    <scp>SAVASI<\/scp>\n                    ; a new self\u2010assessment score in vitiligo"],"prefix":"10.1111","volume":"29","author":[{"given":"L.","family":"Komen","sequence":"first","affiliation":[{"name":"Netherlands Institute for Pigment Disorders\/Department of Dermatology Academic Medical Centre Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.E.","family":"van der Kraaij","sequence":"additional","affiliation":[{"name":"Netherlands Institute for Pigment Disorders\/Department of Dermatology 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