{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T01:23:51Z","timestamp":1768699431210,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Novartis Pharma AG"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Treatment guidelines for chronic spontaneous\/idiopathic urticaria (<jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content>) are available; however, only 50% of patients are well controlled with approved doses of H<jats:sub>1<\/jats:sub>\u2010antihistamines, and certain patients remain symptomatic despite receiving up to 4\u00d7 the approved dose of H<jats:sub>1<\/jats:sub>\u2010antihistamines plus H<jats:sub>2<\/jats:sub>\u2010antihistamines and\/or leucotriene\u2010receptor antagonists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To highlight real\u2010life clinical practice in Taiwan and to understand the unmet medical needs of <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A nationwide cross\u2010sectional, observational survey of 50 dermatologists and 200 <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients was conducted between June 2013 and November 2013. Face\u2010to\u2010face interviews of dermatologists and online interviews of <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients were conducted independently.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Dermatologists reported that dermographism and blood tests were the most commonly used diagnostic methods to confirm the diagnosis. The key driving factor for most clinic\u2010based dermatologists (70%) in choosing a treatment was \u2018response to my medicines\u2019, and most preferred H<jats:sub>1<\/jats:sub>\u2010antihistamines and steroids for treating <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients, whereas most hospital\u2010based dermatologists (85%) gave higher priority to \u2018severity and impact of the conditions\u2019. Patients were reported to have high psychological pressures and significant impact of <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> on their daily activity. In addition, <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients were not satisfied with their current treatment and 69% of patients switched their first\u2010consulted physician. Furthermore, lack of information and concerns about side\u2010effects were major factors which held back patients from seeking Western treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is an unmet medical need of <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patients in Taiwan highlighting gaps among guidelines, real\u2010life clinical practice, patients' perceptions and patients' knowledge of their disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13357","type":"journal-article","created":{"date-parts":[[2015,10,2]],"date-time":"2015-10-02T01:00:36Z","timestamp":1443747636000},"page":"41-49","source":"Crossref","is-referenced-by-count":11,"title":["Unmet medical needs for chronic spontaneous urticaria patients: highlighting the real\u2010life clinical practice in Taiwan"],"prefix":"10.1111","volume":"30","author":[{"given":"Y.\u2010T.","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Dermatology National Taiwan University Hospital and National Taiwan University College of Medicine Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.\u2010C.","family":"Pao","sequence":"additional","affiliation":[{"name":"Novartis Co. 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