{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:51:07Z","timestamp":1790279467253,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T00:00:00Z","timestamp":1449619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Region Zealand Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,6]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Several studies have suggested an association between Hidradenitis Suppurativa (HS) and obesity. Obesity is often expressed as Body Mass Index (\n BMI<\/jats:styled-content>\n ). However,\n BMI<\/jats:styled-content>\n lacks information on body composition. General obesity is a predictor of health status and cardiovascular risk, but body composition (e.g. abdominal fat) may be more so. Basal metabolic rate (\n BMR<\/jats:styled-content>\n ) is an expression of resting metabolism and may serve as a complementary tool when assessing the possibly underlying metabolism behind a persons' body composition.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n To investigate the body composition and basal metabolic rate in individuals with\n HS<\/jats:styled-content>\n compared with healthy controls.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We performed a cross\u2010sectional study on both a hospital\u2010based and population\u2010based\n HS<\/jats:styled-content>\n group and compared with controls using Bioelectrical Impedance Analysis to assess body composition.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We identified a hospital\u2010based\n HS<\/jats:styled-content>\n group of 32 hospital\n HS<\/jats:styled-content>\n patients, a population\u2010based\n HS<\/jats:styled-content>\n group of 430 population\n HS<\/jats:styled-content>\n patients, and 20 780 controls. Age\u2010 and sex\u2010adjusted analyses showed a 10.12% (\n P<\/jats:italic>\n < 0.0001) significantly higher fat percentage in the hospital\u2010based\n HS<\/jats:styled-content>\n group and 3.11% (\n P<\/jats:italic>\n < 0.0001) significantly higher fat percentage for the population\u2010based\n HS<\/jats:styled-content>\n group compared to controls. Correspondingly, the\n HS<\/jats:styled-content>\n groups had a lower muscle percentage (\n P<\/jats:italic>\n < 0.0001) and lower bone mass percentage (\n P<\/jats:italic>\n < 0.0001). Furthermore, visceral fat rating (\n P<\/jats:italic>\n < 0.0001), Body Mass Index (\n P<\/jats:italic>\n < 0.0001), waist circumference (\n P<\/jats:italic>\n < 0.0001), and Waist\/Hip Ratio (\n P<\/jats:italic>\n < 0.0001) was significantly higher in\n HS<\/jats:styled-content>\n patients compared with controls. Additionally, age and sex\u2010adjusted analyses showed a higher predicted estimate of\n BMR<\/jats:styled-content>\n for the\n HS<\/jats:styled-content>\n groups compared with controls (154.56 kcal\/day (95%\n CI<\/jats:styled-content>\n 54.96\u2013254.16) (\n P<\/jats:italic>\n = 0.0031) for the hospital\u2010based\n HS<\/jats:styled-content>\n group, and 82.63 kcal\/day (95%\n CI<\/jats:styled-content>\n 59.70\u2013105.56) (\n P<\/jats:italic>\n < 0.0001) for the population\u2010based\n HS<\/jats:styled-content>\n group).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Hidradenitis Suppurativa is associated with a high fat percentage, high visceral fat, and low muscle percentage adding to the morbidity of\n HS<\/jats:styled-content>\n . The higher predicted estimate of basal metabolic rate (\n BMR<\/jats:styled-content>\n ) in\n HS<\/jats:styled-content>\n patients may reflect a dysfunctional metabolism contributing to the high\u2010fat\u2010body composition.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.13522","type":"journal-article","created":{"date-parts":[[2015,12,10]],"date-time":"2015-12-10T15:56:25Z","timestamp":1449762985000},"page":"980-988","source":"Crossref","is-referenced-by-count":28,"title":["Body composition and basal metabolic rate in Hidradenitis Suppurativa: a Danish population\u2010based and hospital\u2010based cross\u2010sectional study"],"prefix":"10.1111","volume":"30","author":[{"given":"I.M.","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Dermatology Roskilde Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Rytgaard","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.B.","family":"Mogensen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Miller","sequence":"additional","affiliation":[{"name":"Sports Science and Psychology VUC&hf Nordjylland Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.C.","family":"Ring","sequence":"additional","affiliation":[{"name":"Department of Dermatology Roskilde Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ellervik","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Research Nyk\u00f8bing Falster Hospital Nyk\u00f8bing Falster 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