{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:11:04Z","timestamp":1787015464059,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["BMBF\u201001 KI 0501"],"award-info":[{"award-number":["BMBF\u201001 KI 0501"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"publisher","award":["1369\u2010401"],"award-info":[{"award-number":["1369\u2010401"]}],"id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,6]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Human papillomaviruses (\n HPV<\/jats:styled-content>\n ) induce condylomata, anogenital cancers and their precursor lesions as anal or penile intraepithelial neoplasia (\n AIN<\/jats:styled-content>\n \/\n PIN<\/jats:styled-content>\n ).\n HIV<\/jats:styled-content>\n \u2010positive individuals have an increased risk for the development of anogenital\n HPV<\/jats:styled-content>\n \u2010induced lesions.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n Estimation of the prevalence of\n HPV<\/jats:styled-content>\n \u2010related anogenital benign and malignant lesions in\n HIV<\/jats:styled-content>\n \u2010infected men attending a screening programme.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Four hundred\n HIV<\/jats:styled-content>\n \u2010positive men [98% men who have sex with men (\n MSM<\/jats:styled-content>\n )] were enrolled in this prospective study from 2008 to 2011. All patients received an inspection of the anogenital region, digital rectal examination, high\u2010resolution anoscopy (\n HRA<\/jats:styled-content>\n ), anal cytology, anal\/penile histology if required, and\n HPV<\/jats:styled-content>\n \u2010typing of anal and penile swabs.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n At baseline, 75% (\n n<\/jats:italic>\n = 302) of the men had abnormal anal cytological\/histological results. 41% presented with low\u2010grade (\n n<\/jats:italic>\n = 164), 24% with high\u2010grade anal dysplasia (\n n<\/jats:italic>\n = 95) and two men with invasive anal cancer. 2.3% had\n PIN<\/jats:styled-content>\n (\n n<\/jats:italic>\n = 9) and one patient had penile cancer at baseline. Throughout the study period, 75% had anal dysplasia (low\u2010grade\n n<\/jats:italic>\n = 177, high\u2010grade\n n<\/jats:italic>\n = 125), 3.3% (\n n<\/jats:italic>\n = 13) had\n PIN<\/jats:styled-content>\n and two further patients developed anal cancer. Within the study period, 52.8% (\n n<\/jats:italic>\n = 211) had condylomata (49% anal, 15% penile, 11% anal plus penile condylomata). At baseline, 88.5% of anal and 39.3% of penile swabs were\n HPV<\/jats:styled-content>\n \u2010\n DNA<\/jats:styled-content>\n positive, and 77.8% of anal and 26.5% of penile swabs carried high\u2010risk\n HPV<\/jats:styled-content>\n \u2010types.\n HPV<\/jats:styled-content>\n 16 was the most frequent\n HPV<\/jats:styled-content>\n \u2010type.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n HIV<\/jats:styled-content>\n \u2010positive\n MSM<\/jats:styled-content>\n have a high risk for\n HPV<\/jats:styled-content>\n \u2010induced condylomata, (pre)malignant anogenital lesions and anogenital cancers. Screening for\n HPV<\/jats:styled-content>\n \u2010induced dysplasia is crucial to avoid progression to invasive carcinomas. Additionally,\n HPV<\/jats:styled-content>\n \u2010vaccination recommendations should be extended to high\u2010risk populations.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.13539","type":"journal-article","created":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T07:44:46Z","timestamp":1454312686000},"page":"995-1001","source":"Crossref","is-referenced-by-count":36,"title":["The male Screen\n ING<\/scp>\n Study: prevalence of\n HPV<\/scp>\n \u2010related genital and anal lesions in an urban cohort of\n HIV<\/scp>\n \u2010positive men in Germany"],"prefix":"10.1111","volume":"30","author":[{"given":"W.","family":"Fuchs","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Allergology Center for Sexual Health and Medicine Ruhr\u2010University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Wieland","sequence":"additional","affiliation":[{"name":"National Reference Center for Papilloma\u2010 and 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