{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T20:15:00Z","timestamp":1790540100883,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,24]],"date-time":"2016-02-24T00:00:00Z","timestamp":1456272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Galderma R&D SNC"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There is an unmet need for general population\u2010based epidemiological data on rosacea based on contemporary diagnostic criteria and validated population survey methodology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the prevalence of rosacea in the general population of Germany and Russia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>General population screening was conducted in 9\u201310 cities per country to ensure adequate geographic representation. In Part I of this two\u2010phase study, screening of a representative sample of the general population (every fifth person or every fifth door using a fixed\u2010step procedure on a random route sample) was expedited with use of a questionnaire and algorithm based on current diagnostic criteria for rosacea. Of the subjects that screened positive in the initial phase, a randomly selected sample (every third subject) t`hen underwent diagnostic confirmation by a dermatologist in Part <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3052 and 3013 subjects (aged 18\u201365\u00a0years) were screened in Germany and Russia respectively. Rosacea prevalence was 12.3% [95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 10.2\u201314.4] in Germany and 5.0% [95%<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 2.8\u20137.2] in Russia. The profile of subjects with rosacea (75% women; mean age of 40\u00a0years; mainly skin phototype <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, majority of subjects with sensitive facial skin) and subtype distribution were similar. Overall, 18% of subjects diagnosed with rosacea were aged 18\u201330\u00a0years. Over 80% were not previously diagnosed. Within the previous year, 47.5% of subjects had received no rosacea care and 23.7% had received topical and\/or systemic drugs. Over one\u2010third (35% Germany, 43% Russia) of rosacea subjects reported a moderate to severe adverse impact on quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Rosacea is highly prevalent in Germany (12.3%) and Russia (5.0%). The demographic profile of rosacea subjects was similar between countries and the majority were previously undiagnosed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13556","type":"journal-article","created":{"date-parts":[[2016,2,27]],"date-time":"2016-02-27T10:52:08Z","timestamp":1456570328000},"page":"428-434","source":"Crossref","is-referenced-by-count":108,"title":["Prevalence of rosacea in the general population of Germany and Russia \u2013 The <scp>RISE<\/scp> study"],"prefix":"10.1111","volume":"30","author":[{"given":"J.","family":"Tan","sequence":"first","affiliation":[{"name":"University of Western Ontario London Ontario Canada"},{"name":"Windsor Clinical Research Inc Windsor Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Sch\u00f6fer","sequence":"additional","affiliation":[{"name":"Universit\u00e4tshautklinik Klinikum der Goethe Universit\u00e4t Frankfurt\/M Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Araviiskaia","sequence":"additional","affiliation":[{"name":"First Pavlov State Medical University of St\u2010Petersburg St\u2010Petersburg Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Audibert","sequence":"additional","affiliation":[{"name":"Galderma R&amp;D SNC Sophia Antipolis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Kerrouche","sequence":"additional","affiliation":[{"name":"Galderma R&amp;D SNC Sophia Antipolis France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Berg","sequence":"additional","affiliation":[{"name":"Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the RISE study group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/jidsymp.2011.7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.120625"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0856"},{"key":"e_1_2_6_5_1","first-page":"597","article-title":"Rosacea: 244 Tunisian cases","volume":"88","author":"Khaled A","year":"2010","journal-title":"Tunis Med"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000136656"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.05.018"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.04.043"},{"key":"e_1_2_6_9_1","first-page":"419","article-title":"An epidemiological study of rosacea","volume":"69","author":"Berg M","year":"1989","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2014.14087"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.03.023"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/archderm.1988.01670010036018","article-title":"Health effects of sunlight exposure in the United States: results from the first national health and nutrition examination survey 1971\u20101974","volume":"124","author":"Engel A","year":"1988","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_13_1","first-page":"1","article-title":"Prevalence of skin diseases in a population; 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