{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:35:29Z","timestamp":1789684529387,"version":"4.0.1"},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,3,30]],"date-time":"2016-03-30T00:00:00Z","timestamp":1459296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Several cutaneous findings are seen in dialysis dependent chronic kidney disease (CKD) patients. However, there are only a few small studies on cutaneous findings in predialysis CKD patients. We aimed to determine cutaneous findings in predialysis CKD patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional study. Consecutive predialysis CKD patients from nephrology outpatient clinic in a university affiliated hospital were recruited to this study. Detailed dermatologic examination was performed by a senior dermatologist. Blood urea, creatinine, hepatitis B surface antigen and hepatitis C antibody test were studied for each participant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 365 consecutive predialysis CKD patients (stages 2\u20135) included in the study. Three hundred and fifty\u2010eight patients (98.1%) had at least one dermatologic finding. The most common cutaneous finding was xerosis (64.9%) followed by hair findings (41.4%), pruritus (19.2%), pigmentary changes (17.5%), nail findings (15.3%) and oral mucosal findings (9.3%). Longitudinal striations was the most common nail finding, diffuse brown hyperpigmentation was the most common pigmentary change, coated tongue was the most common oral mucosal finding and androgenetic alopecia was the most common hair finding. Frequency and diversity of dermatologic findings did not change across CKD stages.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the largest study investigating dermatologic findings in a well\u2010characterized predialysis CKD patient population. We found that at least one cutaneous finding was present in almost all of the CKD patients. Cutaneous findings are very common and diverse among predialysis CKD patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13643","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T03:42:47Z","timestamp":1459395767000},"page":"1609-1613","source":"Crossref","is-referenced-by-count":14,"title":["Cutaneuos findings in patients with predialysis chronic kidney disease"],"prefix":"10.1111","volume":"30","author":[{"given":"B.","family":"Solak","sequence":"first","affiliation":[{"name":"Department of Dermatology School of Medicine Sakarya University Sakarya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.B.","family":"Acikgoz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine School of Medicine Sakarya University Sakarya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sipahi","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Internal Medicine School of Medicine Sakarya University Sakarya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Sakarya University Sakarya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2015.1024555"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139881003300304"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.97127"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2009.095745"},{"key":"e_1_2_5_6_1","first-page":"365","article-title":"Dermatological disorders in chronic kidney disease with and without maintenance hemodialysis","volume":"52","author":"Shah A","year":"2013","journal-title":"JNMA J Nepal Med Assoc"},{"key":"e_1_2_5_7_1","first-page":"268","article-title":"Skin changes in patients with chronic renal failure","volume":"22","author":"Falodun O","year":"2011","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-158-11-201306040-00007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.077180"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)02478-2"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/17.9.1558"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00433.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2007.0017"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)92337-5"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05900513"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5959.658"},{"key":"e_1_2_5_17_1","first-page":"1417","article-title":"Nail abnormalities: clues to systemic disease","volume":"69","author":"Fawcett RS","year":"2004","journal-title":"Am Fam Physician"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13643","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13643","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.13643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:46:25Z","timestamp":1695570385000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.13643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,30]]},"references-count":16,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/jdv.13643"],"URL":"https:\/\/doi.org\/10.1111\/jdv.13643","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,30]]}}}