{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:32:41Z","timestamp":1761863561292},"reference-count":41,"publisher":"Wiley","issue":"S5","license":[{"start":{"date-parts":[[2016,6,10]],"date-time":"2016-06-10T00:00:00Z","timestamp":1465516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Novartis Pharma AG"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This supplement reports proceedings of the second international Global Urticaria Forum, which was held in Berlin, Germany in November 2015. Despite the clear international guideline, there remain a number of controversies and challenges in the management of patients with chronic urticaria (<jats:styled-content style=\"fixed-case\">CU<\/jats:styled-content>). As a result of major advancements in urticaria over the past 4\u00a0years, the current <jats:styled-content style=\"fixed-case\">EAACI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content><jats:sup>2<\/jats:sup><jats:styled-content style=\"fixed-case\">LEN<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EDF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">WAO<\/jats:styled-content> urticaria guideline treatment algorithm requires updating. Case studies from patients with chronic spontaneous urticaria (<jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content>) [also called chronic idiopathic urticaria (<jats:styled-content style=\"fixed-case\">CIU<\/jats:styled-content>)], chronic inducible urticaria (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>ndU) or diseases and syndromes related to <jats:styled-content style=\"fixed-case\">CU<\/jats:styled-content> are useful in describing and exploring challenges in disease management. Case studies of specific <jats:styled-content style=\"fixed-case\">CSU<\/jats:styled-content> patient populations such as children with <jats:styled-content style=\"fixed-case\">CU<\/jats:styled-content> or patients with angio\u2010edema but no hives also require consideration as potentially challenging groups with unmet needs. The current <jats:styled-content style=\"fixed-case\">EAACI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">GA<\/jats:styled-content><jats:sup>2<\/jats:sup><jats:styled-content style=\"fixed-case\">LEN<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">EDF<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">WAO<\/jats:styled-content> urticaria guideline provides a general framework for the management of patients with <jats:styled-content style=\"fixed-case\">CU<\/jats:styled-content> but, as these cases highlight, a personalized approach based on the expert knowledge of the physician may be required.<\/jats:p>","DOI":"10.1111\/jdv.13696","type":"journal-article","created":{"date-parts":[[2016,6,10]],"date-time":"2016-06-10T21:37:18Z","timestamp":1465594638000},"page":"16-24","source":"Crossref","is-referenced-by-count":9,"title":["Controversies and challenges in the management of chronic urticaria"],"prefix":"10.1111","volume":"30","author":[{"given":"P.","family":"Staubach","sequence":"first","affiliation":[{"name":"Department of Dermatology University Medical Center Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Zuberbier","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Allergie\u2010Centrum\u2010Charit\u00e9 Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Vestergaard","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Aarhus University Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Siebenhaar","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Allergie\u2010Centrum\u2010Charit\u00e9 Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Toubi","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology Bnai\u2010Zion Medical Center Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Sussman","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology St. Michael's Hospital and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2005.00964.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12313"},{"key":"e_1_2_9_4_1","unstructured":"European Medicines Evaluation Agency (EMEA).Omalizumab (Xolair) summary of product characteristics (SmPC). 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