{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T04:15:27Z","timestamp":1749096927682,"version":"3.41.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T00:00:00Z","timestamp":1471046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["N N402 374039"],"award-info":[{"award-number":["N N402 374039"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Microchimerism is defined as a stable presence of low numbers of cells derived from a different individual due to cell transfer between twins or between mother and fetus during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Fetal cells in the organism of the mother (<jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>c) are postulated to play a role in autoimmune diseases. Psoriasis is a disease which has an autoimmune component, but no study on microchimerism in this disease has been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The easiest way to detect microchimerism is to look for male cells in blood or other tissues of a woman who previously delivered a son. Here, we looked for the presence of male cells in mononuclear cell subpopulations from peripheral blood and in skin samples of women with psoriasis and of healthy women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We detected<jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>c in similar proportions of patients and controls in<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4+,<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>8+ and<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>34+ cells, whereas in<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>34\u2010 cells they were present in higher fraction of controls, and similar but non\u2010significant difference was observed in<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>19+ cells. No microchimeric cells were detected in patients' skin samples, both from affected and non\u2010affected skin, or in skin tissue from healthy control individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our result does not prove the involvement of microchimerism in the aetiology of psoriasis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13781","type":"journal-article","created":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T11:02:43Z","timestamp":1471086163000},"page":"114-118","source":"Crossref","is-referenced-by-count":0,"title":["Lack of detectable fetal microchimerism in psoriasis vulgaris lesions and in non\u2010affected skin in spite of its presence in peripheral blood<scp>CD<\/scp>34\u2010positive and<scp>CD<\/scp>34\u2010negative cells"],"prefix":"10.1111","volume":"31","author":[{"given":"W.","family":"Niepiek\u0142o\u2010Miniewska","sequence":"first","affiliation":[{"name":"Laboratory of Immunogenetics and Tissue Immunology Ludwik Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Baran","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, Venereology and Allergology Wroc\u0142aw Medical University Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.C.","family":"Szepietowski","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, Venereology and Allergology Wroc\u0142aw Medical University Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Nowakowska","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics and Tissue Immunology Ludwik Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Ku\u015bnierczyk","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics and Tissue Immunology Ludwik Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2012.10.011"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2012.08.004"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-009-0044-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2012.03.002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.02.002"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2011.11.001"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2011.10.003"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181eb2eb4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i6.1510"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2010.05.006"},{"key":"e_1_2_6_12_1","unstructured":"McKusickVA.Sex\u2010determining region Y; SRY. 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