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Aim of this study was to summarize the most recent data about <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content> which aimed at establishing the nosological position of palmoplantar pustulosis. A systematic search of published literature was carried out. General characteristics of patients with <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content> in different populations were present. We reviewed histological, immunological and genetic studies, as well as treatment options for <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content> presents with clinical features, which are not present in psoriasis; however, the common coexistence of psoriasis vulgaris and\/or positive family history for psoriasis indicates at least a close relationship between <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content> and psoriasis. At present, there are not sufficient data to exclude <jats:styled-content style=\"fixed-case\">PPP<\/jats:styled-content> from psoriasis group.<\/jats:p>","DOI":"10.1111\/jdv.13846","type":"journal-article","created":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T11:02:42Z","timestamp":1471086162000},"page":"38-44","source":"Crossref","is-referenced-by-count":54,"title":["What do we know about palmoplantar pustulosis?"],"prefix":"10.1111","volume":"31","author":[{"given":"M.","family":"Misiak\u2010Galazka","sequence":"first","affiliation":[{"name":"Department of Dermatology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Wolska","sequence":"additional","affiliation":[{"name":"Department of Dermatology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Rudnicka","sequence":"additional","affiliation":[{"name":"Department of Dermatology 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