{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:54:56Z","timestamp":1791276896406,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T00:00:00Z","timestamp":1471046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T00:00:00Z","timestamp":1471046400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,2]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Information on frequency of melanoma and its clinicopathological subtypes derived from dermatology clinics in Turkey is limited.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n As data about melanoma show clear differences due to geographic and ethnic distribution, we scrutinized the rich data of our dermatology centre in Istanbul.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Consecutive patients diagnosed with melanoma in a tertiary dermatology clinic during the last 19 years were retrospectively investigated about the clinical presentation of the skin lesions during admission, frequency of subtypes and localization of the tumour.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were 227 patients with melanoma showing five different clinical presentations: 200 of them had totally 207 primary cutaneous melanoma (\n PCM<\/jats:styled-content>\n ) lesions, nine had\n PCM<\/jats:styled-content>\n lesions associated with metastatic skin lesions, three presented with local recurrence, eight with only skin metastases and seven with regressed skin melanoma following systemic melanoma metastases. Histologically, 23.19% of the\n PCM<\/jats:styled-content>\n lesions were intraepidermal (\n in situ<\/jats:italic>\n ) and Breslow thickness was less than 1 mm in 30.9% of the patients with invasive melanoma. The most common subtype was superficial spreading melanoma (\n SSM<\/jats:styled-content>\n ) (37.19%), followed by lentigo malignant melanoma (\n LMM<\/jats:styled-content>\n ) (31.4%), acral lentiginous melanoma (\n ALM<\/jats:styled-content>\n ) (19.32%) and nodular melanoma (\n NM<\/jats:styled-content>\n ) (6.76%). Head and neck region was the most common (34.78%) localization of\n PCM<\/jats:styled-content>\n lesions.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Different clinical presentations, including various types of cutaneous melanoma metastases, were seen. However, a great proportion of our patients were relatively early diagnosed, either having an\n in situ<\/jats:italic>\n or an invasive\n PCM<\/jats:styled-content>\n with a Breslow thickness \u22641 mm. Even though\n SSM<\/jats:styled-content>\n was the most common subtype of\n PCM<\/jats:styled-content>\n in our series, its rate was lower compared to many European countries. Furthermore, the rate of\n NM<\/jats:styled-content>\n subtype was also low, while\n LMM<\/jats:styled-content>\n and\n ALM<\/jats:styled-content>\n rates were higher in comparison to studies originating from European countries. This striking discrepancy requires further studies to explain the probable causes.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jdv.13866","type":"journal-article","created":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T06:56:44Z","timestamp":1471071404000},"page":"236-240","source":"Crossref","is-referenced-by-count":12,"title":["An update on cutaneous melanoma in Turkey: evaluation of 19\u2010year data in a single tertiary centre and review of the literature"],"prefix":"10.1111","volume":"31","author":[{"given":"C.","family":"Baykal","sequence":"first","affiliation":[{"name":"Departments of Dermatology & Venereology Istanbul Medical Faculty Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Atci","sequence":"additional","affiliation":[{"name":"Departments of Dermatology & Venereology Istanbul Medical Faculty Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Polat Ekinci","sequence":"additional","affiliation":[{"name":"Departments of Dermatology & Venereology Istanbul Medical Faculty Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Buyukbabani","sequence":"additional","affiliation":[{"name":"Department of Pathology Istanbul Medical Faculty Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13671-012-0035-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-14-0295"},{"key":"e_1_2_5_4_1","first-page":"190","article-title":"Dermatoloji polikliniklerinin 5 y\u0131ll\u0131k malign melanom olgular\u0131n\u0131n de\u011ferlendirilmesi","volume":"30","author":"Baykal C","year":"1996","journal-title":"Turkderm"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.23.10451"},{"key":"e_1_2_5_6_1","first-page":"1137","article-title":"Cutaneous melanoma in Turkey: analysis of 1157 patients in the Melanoma Turkish Study","volume":"20","author":"Abali H","year":"2015","journal-title":"J BUON"},{"key":"e_1_2_5_7_1","first-page":"130","article-title":"Haydarpa\u015fa Numune hastanesinde 5 y\u0131ll\u0131k malign melanom olgular\u0131n\u0131n de\u011ferlendirilmesi","volume":"8","author":"Ayd?ngoz IE","year":"1998","journal-title":"T\u00fcrkiye Klinikleri Journal of Dermatology"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2013.14.1.533"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01507.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.047"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12561"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04021.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12007"},{"key":"e_1_2_5_14_1","first-page":"271","article-title":"Clinical and morphological characteristics of cutaneous melanoma","volume":"22","author":"Balaban J","year":"2014","journal-title":"Acta Dermatovenerol Croat"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12496"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000300006"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70251-3"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2004.01644.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2008.09.001"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21254"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11125.x"},{"key":"e_1_2_5_22_1","first-page":"1","article-title":"Melanoma\u2010clinical, dermatoscopical, and histopathological morphological characteristics","volume":"22","author":"Situm M","year":"2014","journal-title":"Acta Dermatovenerol Croat"},{"key":"e_1_2_5_23_1","unstructured":"Weather Averages for Turkey.Current results weather and science facts. 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