{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:52:16Z","timestamp":1771674736030,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,9,12]],"date-time":"2016-09-12T00:00:00Z","timestamp":1473638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acad Dermatol Venereol"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Phototherapy is the preferred treatment modality for active and generalized vitiligo. One of the widely accepted consensus on starting dose of phototherapy is using a uniform dose of 280 mJ\/cm<jats:sup>2<\/jats:sup> regardless of patients' Fitzpatrick skin phototype (SPT). However, in many clinical experiences with Asian vitiligo patients, the protocol seems suboptimal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To gather more evidence on establishing a higher starting dosage for Asian vitiligo patients undergoing phototherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled generalized vitiligo patients with lesions sized adequate enough for phototest. Minimal erythema dose (MED) of vitiligo lesion and non\u2010lesion was measured along with melanin index (MI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Relatively, a wide range of MED and MI was observed even among patients with similar SPT. The range of MED for lesional skin was 300\u2013700 mJ\/cm<jats:sup>2<\/jats:sup> and the MED for non\u2010lesion was 500\u2013800 mJ\/cm<jats:sup>2<\/jats:sup>. Correlation was noted between lesional MED and non\u2010lesional MI (Spearman correlation, \u03c1 = 0.664 [<jats:italic>P<\/jats:italic> &lt; 0.036]) and mean lesional MED was approximately 65% of mean non\u2010lesional MED.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Results from phototest and tolerability of patients to doses higher than 280 mJ\/cm<jats:sup>2<\/jats:sup> may indicate that higher starting doses might be appropriate for Asian vitiligo patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jdv.13933","type":"journal-article","created":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T07:26:40Z","timestamp":1471937200000},"page":"894-897","source":"Crossref","is-referenced-by-count":5,"title":["Investigation of suitable starting doses of narrowband UVB in Asian vitiligo patients: a pilot study"],"prefix":"10.1111","volume":"31","author":[{"given":"H.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.H.","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Severance Hospital Cutaneous Biology Research Institute Yonsei University College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-148X.2012.00997.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.06.002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670060015008"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.03958.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12130"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.1997.tb00233.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01250.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0846.2000.006004230.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2002.14.2.71"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000211297"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2004.tb01273.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12874671"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00714.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04343.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550410022203"}],"container-title":["Journal of the European Academy of Dermatology and Venereology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjdv.13933","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jdv.13933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T13:38:23Z","timestamp":1695044303000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jdv.13933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,12]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/jdv.13933"],"URL":"https:\/\/doi.org\/10.1111\/jdv.13933","archive":["Portico"],"relation":{},"ISSN":["0926-9959","1468-3083"],"issn-type":[{"value":"0926-9959","type":"print"},{"value":"1468-3083","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,12]]}}}